2,3-dimethyl-6-nitro-2H-indazole

2,3-dimethyl-6-nitro-2H-indazole 구조식 이미지
카스 번호:
444731-73-1
상품명:
2,3-dimethyl-6-nitro-2H-indazole
동의어(영문):
Pazopanib Impurity 19;3-Methly-6-nitroindazole;2,3-dimethyl-6-nitrobazole;2,3-Dimethyl-6-nitro-1H-i...;2,3-dimethyl-6-nitro-indazole;3-diMethyl-6-nitro-2H-indazole;2,3-dimethyl-6-nitro-1H-indazole;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE;2H-Indazole, 2,3-diMethyl-6-nitro-;2,3-DIMETHYL-6-NITRO-2H-INDAZOLE ISO 9001:2015 REACH
CBNumber:
CB82455022
분자식:
C9H9N3O2
포뮬러 무게:
191.19
MOL 파일:
444731-73-1.mol

2,3-dimethyl-6-nitro-2H-indazole 속성

녹는점
183-186°C
끓는 점
377.0±22.0 °C(Predicted)
밀도
1.36±0.1 g/cm3(Predicted)
저장 조건
Sealed in dry,Room Temperature
용해도
DMSO(약간 용해됨), 메탄올(약간 용해됨)
산도 계수 (pKa)
-0.55±0.30(Predicted)
물리적 상태
고체
물리적 상태
단단한 모양
색상
노란색

안전

2,3-dimethyl-6-nitro-2H-indazole C화학적 특성, 용도, 생산

용도

2,3-Dimethyl-6-nitro-2H-indazole is an impurity in the synthesis of Pazopanib (P210925) hydrochloride, an oral angiogenesis inhibitor targeting VEGFR and PDGFR.

structure and hydrogen bonding

In the mol-ecule of 2,3-dimethyl-6-nitro-2H-indazole, C9H9N3O2, the indazole ring system is almost planar [maximum deviation = 0.019 (3) Å for the C atom bearing the nitro group]. In the crystal structure, inter-molecular C—H...O inter-actions link the mol-ecules into centrosymmetric dimers, forming R 2 2(18) ring motifs. Aromatic π–π contacts between indazole rings [centroid–centroid distances = 3.632 (1) and 3.705 (1)?] may further stabilize the structure[1].
2,3-DIMETHYL-6-NITRO-2H-INDAZOLE

2,3-dimethyl-6-nitro-2H-indazole 준비 용품 및 원자재

원자재

준비 용품


2,3-dimethyl-6-nitro-2H-indazole 공급 업체

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