Cyclosporin H
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Cyclosporin H 속성
- 녹는점
- 148-151°C
- 끓는 점
- 1293.8±65.0 °C(Predicted)
- 밀도
- 1.016±0.06 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- 클로로포름(약간 용해됨), 메탄올(약간 용해됨, 가열, 초음파 처리)
- 산도 계수 (pKa)
- 13.32±0.70(Predicted)
- 물리적 상태
- 가루
- 색상
- 흰색에서 베이지색
- optical activity
- [α]/D -100 to -115°, c = 0.5 in methanol
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| HS 번호 | 29420000 |
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Cyclosporin H C화학적 특성, 용도, 생산
개요
Cyclosporin H is a natural cyclic undecapeptide that selectively antagonizes the formyl peptide receptor at concentrations ranging from 0.1 to 10 μM. Unlike cyclosporin A , cyclosporin H does not bind cyclophilin to evoke an immunosuppressant response. Cyclosporin H has been reported to inhibit phorbol ester-mediated effects in mouse skin and block calcium/calmodulin-dependent EF-2 phosphorylation in vitro.화학적 성질
White Powder용도
Cyclosporin H is a minor analogue of the cyclosporin family which is immunologically inactive as it does not bind to immunophilin. Cyclopsorin H is the most extensively investigated of the minor cyclosporin analogues and displays a range of activities. It is a potent inhibitor of tumour-promoting phorbol esters on mouse skin in vivo, and of calcium/calmodulin-dependent EF-2 phosphorylation in vitro, a potent and selective antagonist of formyl peptide receptor and inhibitor of formyl peptide-induced superoxide formation.Cyclosporin H 준비 용품 및 원자재
원자재
준비 용품
Cyclosporin H 공급 업체
글로벌( 167)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shenzhen Excellent Biomedical Technology Co.,Ltd. | +86-0755-26050679 +86-15915472436 |
sale@ex-biotech.cn | China | 1031 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 24738 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
| Standardpharm Co. Ltd. | 86-714-3992388 |
overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 |
ramyan@ex-biotech.com | CHINA | 954 | 58 |
| Qingdao kaimoshi biochemical technology co., ltd. | +86-0571-87191913 +86-19957014543 |
info@kaimosi.com | CHINA | 144 | 58 |
| SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |