포스트리신나트륨소금
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포스트리신나트륨소금 속성
- 저장 조건
- -20°C
- 용해도
- Soluble in H2O
- 물리적 상태
- 무색 고체
- 수용성
- 물에 100mM까지 용해됨
- InChIKey
- GMNLFZGMQHSFFV-DSXPUHJBNA-N
- SMILES
- [C@@H](OP(O)(O)=O)(C[C@@H](O)/C=C\C=C/C=C/CO)[C@@](O)(C)/C=C/[C@H]1CC=CC(=O)O1.[NaH] |&1:0,7,17,22,r|
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 | ||
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RTECS 번호 | UQ0600000 |
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유해·위험 문구: |
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예방조치문구: |
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포스트리신나트륨소금 C화학적 특성, 용도, 생산
개요
Fostriecin is an inhibitor of the serine/threonine protein phosphatases 2A (PP2A) and 4 (PP4) (IC50s = 3.2 and 3 nM, respectively). It less effectively inhibits topoisomerase II and PP1 (IC50s = 40 and 131 μM, respectively) and does not inhibit PP2B. Through its effects on protein phosphatases, fostriecin increases the level of histone H3 phosphorylation and may alter epigenetic regulation of cell proliferation. On a related note, fostriecin was first identified as an antitumor antibiotic.용도
Antineoplastic. Fostriecin is a Topo II, PP1, and PP2A inhibitor.생물학적 활성
Originally identified as an antitumor antibiotic from Streptomyces pulveraceous . Displays potent inhibition of protein phosphatase types 2A (PP2A) and 4 (PP4) with IC 50 values of 1.5 nM and 3 nM respectively. Also exhibits weaker inhibition of topoisomerase II (IC 50 = 40 μ M) and protein phosphatase type 1 (PP1) (IC 50 = 131 μ M) with no apparent inhibition of protein phosphatase type 2B (PP2B). Active in vivo .포스트리신나트륨소금 준비 용품 및 원자재
원자재
준비 용품
포스트리신나트륨소금 공급 업체
글로벌( 63)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Zhuzhou Yaozhijie Chemical Co., LTD | +8618073316972 |
sales@goodpeptides.com | China | 244 | 58 |
Hubei Lange Biotechnology Co., Ltd. | +8617762501948 |
sales2@langebiotech.com | China | 154 | 58 |
Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
zhuzhou dingcheng meihei comestic co.,ltd | +8618873369619 |
dingchengbusiness8@163.com | China | 260 | 58 |
Shanghai Getian Industrial Co., LTD | +86-15373193816 +86-15373193816 |
mike@ge-tian.com | China | 269 | 58 |
.GZ HONESTCHEM CO.,LTD | +86-15013270415 |
honestchemical@foxmail.com | China | 246 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-87569265 +86-15319487004 |
1015@dideu.com | China | 2132 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 |
laboratory@coreychem.com | China | 30250 | 58 |
Qiuxian Baitai New Material Co., LTD | +8618330912755 |
sale2@hbyalin.com | China | 1677 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 |
1026@dideu.com | China | 7830 | 58 |
포스트리신나트륨소금 관련 검색:
MEPARTRICIN
21-hydroxyoligomycin A
anguinomycin A
Hexacyclinic acid
KAZUSAMYCIN A FROM STREPTOMYCES SP.
echinosporin
Daunorubicin hydrochloride
herbimycin C
KIGAMICIN C
PD 124895
Cladospirone bisepoxide
Cochliodinol,fromChaetomiumglobosum.
6H-Benzo(d)naphtho(1,2-b)pyran-6-one, 4-(6-deoxy-alpha-galactofuranosy l)-1-hydroxy-10,12-dimethoxy-8-methyl-
FOSTRIECIN SODIUM SALT
Fostriecin
Fostriecin, Streptomyces pulveraceous
Fostriecin,StreptomycesPulveraceoussubsp.Fostreus
FOSTRIECIN