인산트리크레질
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인산트리크레질 속성
- 녹는점
- <-40°C
- 끓는 점
- 265 °C10 mm Hg(lit.)
- 밀도
- 1.143 g/mL at 25 °C(lit.)
- Pour Point
- -28
- 증기압
- 0.03 mm Hg ( 25 °C)
- 굴절률
- n
20/D 1.555(lit.)
- 인화점
- >230 °F
- 저장 조건
- Store below +30°C.
- 용해도
- 유기 용매: 그것과 섞일 수 있습니다 (lit.)
- 물리적 상태
- 가루
- 색상
- 흰색에서 황백색까지
- 수용성
- 불용성
- Merck
- 14,9763
- Dielectric constant
- 4.0(80℃)
- 안정성
- 안정적인. 강한 산화제와 호환되지 않습니다. 일부 플라스틱을 부드럽게 할 수 있습니다. 알칼리성 조건에서 천천히 가수분해됩니다.
- InChIKey
- ISNNXHQBIBWQHG-UHFFFAOYSA-N
- LogP
- 5.93
- CAS 데이터베이스
- 1330-78-5(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,N,T | ||
---|---|---|---|
위험 카페고리 넘버 | 21/22-51/53-39/23/24/25-62-50/53 | ||
안전지침서 | 28-61-45-28A-20/21-60-36/37 | ||
유엔번호(UN No.) | UN 2574 6.1/PG 2 | ||
WGK 독일 | 2 | ||
RTECS 번호 | TD0175000 | ||
자연 발화 온도 | 770 °F | ||
TSCA | Yes | ||
HS 번호 | 2919 90 00 | ||
위험 등급 | 6.1 | ||
포장분류 | II | ||
유해 물질 데이터 | 1330-78-5(Hazardous Substances Data) | ||
독성 | cat,LD50,skin,1500mg/kg (1500mg/kg),BEHAVIORAL: ATAXIAPERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE),Toxicology Letters. Vol. 1000(Sp, | ||
기존화학 물질 | KE-28648 |
인산트리크레질 C화학적 특성, 용도, 생산
화학적 성질
Tricresyl phosphate is an isomeric mixture of phosphoric acid esters of cresols. It is an odourless and colourless oily liquid (molar mass 368.4 g/mol, melting point –33°C).Tricresyl phosphates were used as flame retardants and plasticisers in PVC, nitrocellulose and acrylates.
용도
Tricresyl phosphate (TCP) is used as a solvent for nitrocellulose esters and numerous natural resins. It is a plasticizer for chlorinated rubber, vinyl plastics, polystyrene and polyacrylic and polymethacrylic esters. Tricresyl phosphate also acts as a binder for resins and nitrocellulose to improve toughness, elasticity and polishing properties of coatings. Alone or associated with hydrocarbons, it is used as an antiwear and antifriction additive in numerous synthetic lubricants, incorrectly termed “oils” by reason of their appearance. It is also employed as a hydraulic fluid. When incorporated in gasoline, tricresyl phosphate counteracts the harmful effects of lead deposits. In addition, it is an excellent fire retardant in many industries.Usually used as a mediator in the preparation of uranium-sensitive electrode based on membrane containing uranium di-(4-octylphenyl)phosphate as sensor.
제조 방법
Tricresyl phosphate is prepared by reaction of cresols with phosphorus oxychloride, phosphoric acid, or phosphorus pentachloride:OPCl3 + 3 HOC6H4CH3 → OP(OC6H4CH3)3 + 3 HCl
The grades of cresol commonly is a mixture of three isomers (o-, m-, p-). The fact that tricresyl phosphate is derived from a mixture and itself is a mixture ensures that it remains liquid over a wide span of temperatures.
A "refined grade" of tricresyl phosphate is prepared by vacuum distillation, or alternatively by washing with 2% sodium hydroxide and water.
건강위험
The tricresyl phosphates (TCPs) are part of a series of organophosphorus compounds which have been shown to cause delayed neurotoxicity. The 1930 outbreak of “ginger jake” paralysis was caused by the contamination of ginger extract by cresyl phosphates, used in the processing of the spice. Since that time, there have been several incidents reported of accidental poisoning of food by tri-o-cresyl phosphate (TOCP). There are few case series reports of occupational exposure in the literature. Acute occupational exposures have been described as causing gastrointestinal symptoms followed by a latent period of days to 4 weeks, after which extremity pain and tingling progress to motor paralysis of the lower extremities up to the thighs, and of the upper extremities to the elbow. There is rarely sensory loss. Partial to total recovery may take years. Fatalities have occurred in high-dose ingestion.Safety Profile
Moderately toxic by ingestion and skin contact. Human systemic effects by ingestion: flaccid paralysis without anesthesia, motor activity changes, and muscle weakness. An experimental teratogen. Experimental reproductive effects. An eye and skin irritant. Combustible. When heated to decomposition it emits toxic fumes of POx.잠재적 노출
According to the World Health Organization there is no safe level of exposure to Tricresyl Phosphate(TCP).TCP has been used as a flame retardant in fabric, plastics and rubbers and as a plasticizer in PVC, lacquers, varnishes and nitrocellulose. It is also used as a heat exchange medium and hydraulic fluid. TCP was detected in all house dust samples gathered in two different North American studies.Biomonitoring studies detected TCP in the breast milk of women in Asia and Sweden. EPA has characterized TCP to exhibit moderate persistence in the environment based on biodegradation studies.
Purification Methods
Dry the ester with CaCl2, percolate it through a column of alumina, then distil it under a vacuum. Alernatively pass it through a packed column of alumina at 150o, with a counter-current stream of nitrogen, under reduced pressure, to remove residual traces of volatile impurities. It also crystallises from pet ether (b 60-80o). [Cherbuliez in Organic Phosphorus Compounds (Kosolapoff & Maier eds) Wiley-Interscience Vol 6 pp 454-457 1973.]인산트리크레질 준비 용품 및 원자재
원자재
준비 용품
인산트리크레질 공급 업체
글로벌( 271)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 |
sales@hbmojin.com | China | 12446 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 |
sales1@chuanghaibio.com | China | 5892 | 58 |
Changzhou waston chemical technology Co.,Ltd | +86-051985861892 +8618112881323 |
info@wastonchem.com | China | 250 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 20291 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21666 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +8618949832763 |
info@tnjchem.com | China | 2989 | 55 |
Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 564 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8820 | 58 |