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아세트산 칼슘

아세트산 칼슘
아세트산 칼슘 구조식 이미지
카스 번호:
62-54-4
한글명:
아세트산 칼슘
동의어(한글):
아세트산칼슘;아세트산칼슘;칼슘아세테이트
상품명:
Calcium acetate
동의어(영문):
teltozan;FEMA 2228;RWPE2 Cell;limeacetate;grayacetate;brownacetate;vinegarsalts;sorbo-calcion;Calciumacetat;MAGGRAN(R) CA
CBNumber:
CB8312095
분자식:
C4H6CaO4
포뮬러 무게:
158.17
MOL 파일:
62-54-4.mol

아세트산 칼슘 속성

녹는점
160°C (dec.)
밀도
1,5 g/cm3
굴절률
1.5500
FEMA
2228 | CALCIUM ACETATE
인화점
160°C
용해도
H2O: 1 M at 20 °C, clear, colorless
물리적 상태
Powder
색상
white
수용성
soluble
분해온도
160 ºC
안정성
Stable. Non-flammable. Incompatible with strong oxidizing agents.
InChIKey
VSGNNIFQASZAOI-UHFFFAOYSA-L
CAS 데이터베이스
62-54-4(CAS DataBase Reference)
EPA
Calcium acetate (62-54-4)

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 26-36
WGK 독일 1
RTECS 번호 AF7525000
TSCA Yes
HS 번호 29152990
유해 물질 데이터 62-54-4(Hazardous Substances Data)

아세트산 칼슘 MSDS


Acetic acid calcium salt

아세트산 칼슘 C화학적 특성, 용도, 생산

개요

Calcium acetate is a chemical compound which is calcium salt of acetic acid. It has the formula Ca(C2H3O2)2. Its standard name is calcium acetate, while calcium ethanoate is the systematic name. An older name is acetate of lime. The anhydrous form is very hygroscopic; therefore the monohydrate (Ca(CH3COO)2?H2O) is the common form.

화학적 성질

Calcium acetate occurs as a white or almost white, odorless or almost odorless, hygroscopic powder.

용도

Calcium Acetate is the calcium salt of acetic acid which functions as a sequestrant and mold control agent. it contains approximately 25% calcium. it is a white odorless powder which is readily soluble in water with a solubility of approximately 37 g in 100 g water at 0°c. its solubility decreases with increasing temperature, with a sol- ubility of approximately 29 g in 100 g of water at 100°c.

용도

Calcium Acetate is the salt of acetic acid which is used as a preservative and sequestrant.

정의

ChEBI: The calcium salt of acetic acid. It is used, commonly as a hydrate, to treat hyperphosphataemia (excess phosphate in the blood) in patients with kidney disease: the calcium ion combines with dietary phosphate to form (insoluble) calcium phosphate, which is excreted in the faeces.

생산 방법

Calcium acetate can be prepared by soaking calcium carbonate (found in eggshells, or in common carbonate rocks such as lime stone or marble) in vinegar:
CaCO3 + 2CH3COOH → Ca(CH3COO)2 + H2O + CO2
Since both reagents would have been available pre-historically, the chemical would have been observable as crystals then.

제조 방법

Produced by calcium hydroxide neutralization of acetic acid.

Pharmaceutical Applications

Calcium acetate is used as a preservative in oral and topical formulations.
Therapeutically, parenteral calcium acetate acts as a source of calcium ions for hypocalcemia or electrolyte balance. Oral calcium acetate is used as a complexing agent for hyperphosphatemia in dialysis patients. Calcium acetate is also used in the food industry as a stabilizer, buffer and sequestrant.

Safety Profile

Poison by intravenous and intraperitoneal routes. Mutation data reported. See also CALCIUM COMPOUNDS. When heated to decomposition it emits acrid smoke and fumes.

Safety

Calcium acetate is used in oral and topical formulations. The pure form of calcium acetate is toxic by IP and IV routes.
LD50 (mouse, IP): 0.075 g/kg
LD50 (mouse, IV): 0.052 g/kg
LD50 (rat, oral): 4.28 g/kg

Veterinary Drugs and Treatments

Calcium acetate can be used for oral administration to treat hyperphosphatemia in patients with chronic renal failure. Secondary to its phosphorus binding efficiency and lower concentration of elemental calcium, calcium acetate is considered the most effective and having the lowest potential for causing hypercalcemia of the calcium-based phosphorus-binding agents. When compared to calcium carbonate, calcium acetate binds approximately twice as much phosphorus per gram of elemental calcium administered. Unlike calcium citrate, calcium acetate does not promote aluminum absorption.

저장

Calcium acetate is stable although very hygroscopic, and so the monohydrate is the common form. It decomposes on heating (above 1608℃) to form calcium carbonate and acetone.
Store in well-closed airtight containers.

Purification Methods

Recrystallise it from water (3mL/g) by partial evaporation in a desiccator. [Beilstein 2 IV 113.]

비 호환성

Calcium acetate is incompatible with strong oxidizing agents and moisture.

Regulatory Status

GRAS listed. Accepted for use as a food additive in Europe. Included in the FDA Inactive Ingredients Database (oral suspensions and tablets; topical emulsions, lotions, and creams). Included in nonparenteral medicines (oral tablets) licensed in the UK.

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