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NFPA 704
0
2
0
CeMMEC1 C화학적 특성, 용도, 생산
개요
CeMMEC1 is an N-methylisoquinolinone that inhibits the second bromodomain of TAF1 (Kd = 1.8 μM; IC50 = 0.9 μM). It does not bind to either the first or second bromodomain of BRD4. This compound synergizes with (+)-JQ1 to inhibit the proliferation of THP-1 and H23 lung adenocarcinoma cells.
용도
CeMMEC1, shows high affinity for TAF1, and is an inhibitor of BRD4.
