C2 CERAMIDE

C2 CERAMIDE 구조식 이미지
카스 번호:
3102-57-6
상품명:
C2 CERAMIDE
동의어(영문):
N-ACETYLSPHINGOSINE;N-ACETYL-D-SPHINGOSINE;N-ETHANOYL-D-ERYTHRO-SPHINGOSINE;CERAMIDE C2;C2 CERAMIDE;C2:0 CERAMIDE;TOC Ceramide;ACETYL CERAMIDE;C14 SPHINGOID BASE;N-Acetylsphigosine
CBNumber:
CB8342539
분자식:
C20H39NO3
포뮬러 무게:
341.53
MOL 파일:
3102-57-6.mol

C2 CERAMIDE 속성

녹는점
93-96 °C
끓는 점
477.13°C (rough estimate)
밀도
1.0283 (rough estimate)
굴절률
1.5614 (estimate)
저장 조건
−20°C
용해도
DMSO: 용해될 수 있다
산도 계수 (pKa)
13.50±0.20(Predicted)
물리적 상태
가루
색상
하얀색
안정성
수분에 민감한

안전

안전지침서 22-24/25
WGK 독일 3
HS 번호 29241990

C2 CERAMIDE C화학적 특성, 용도, 생산

개요

C2 ceramide is a cell-permeable analog of naturally occurring ceramides. It mediates many diverse biological activities, as do natural ceramides. These processes include differentiation of HL-60 cells, induction of apoptosis, activation of protein phosphatase 2A, and inhibition of the mitochondrial respiratory chain. C2 ceramide also enhances the expression of COX-2 in human dermal fibroblasts and stimulates the growth of bovine aortic smooth muscle cells. The ability of C2 ceramide to destabilize membranes may be responsible for its inhibition of platelet aggregation.

화학적 성질

White Crystalline Solid

용도

A biologically active, cell permeable, but nonphysiologic ceramide analog. It inhibits cell proliferation and induces monocytic differentiation of HL-60 cells and induces apoptosis. It stimulates protein phosphatase 2A and activates MAP Kinase2

생물학적 활성

A potent modulator of cell proliferation and differentiation. Activates protein phosphatase-1 (PP1) and -2A (PP2A), as well as ceramide-activated protein phosphatase (CAPP) in vitro .

C2 CERAMIDE 준비 용품 및 원자재

원자재

준비 용품


C2 CERAMIDE 공급 업체

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TargetMol Chemicals Inc.
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GIHI CHEMICALS CO.,LIMITED
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LEAPCHEM CO., LTD.
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J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
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Meryer (Shanghai) Chemical Technology Co., Ltd. 4006608290; 18621169109
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