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PICEATANNOL

PICEATANNOL 구조식 이미지

카스 번호:: 10083-24-6

상품명:: PICEATANNOL

동의어(영문):: Piceatanl;NSC-622471;PICEATANNOL;Astringenin;Beryl alcohol;20MG/50MG/100G;Piceatannol>Piceatannol,96%;(E)-Piceatannol;trans-Piceatannol

CBNumber:: CB8377487

분자식:: C14H12O4

포뮬러 무게:: 244.24

MOL 파일:: 10083-24-6.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 349

PICEATANNOL 속성

녹는점: 223.0-227.0 °C

끓는 점: 108°C/0.04mmHg(lit.)

밀도: 1.1245 (rough estimate)

굴절률: 1.5190 (estimate)

저장 조건: 2-8°C

용해도: H₂O: 0.5 mg/mL

물리적 상태: 가루

산도 계수 (pKa): 9.17±0.10(Predicted)

색상: 연한 황갈색에서 노란색까지

최대 파장(λmax): 323nm(MeOH)(lit.)

안정성: 제공된 대로 구매일로부터 2년 동안 안정적입니다. DMSO 또는 에탄올 용액은 -20°에서 최대 2개월 동안 보관할 수 있습니다.

LogP: 2.690 (est)

안전

안전지침서	24/25
WGK 독일	3
HS 번호	29072990

PICEATANNOL C화학적 특성, 용도, 생산

화학적 성질

yellow to golden or green crystalline powder

용도

A human metabolite of Resveratrol (R150000). Piceatannol is strong anti-oxidant.

정의

ChEBI: A stilbenol that is trans-stilbene in which one of the phenyl groups is substituted by hydroxy groups at positions 3 and 4, while the other phenyl group is substituted by hydroxy groups at positions 3 and 5.

일반 설명

A cell-permeable, substrate competitive and reversible plant metabolite that inhibits the activity of rat liver protein kinase A catalytic subunit (IC₅₀ = 3 μM), PKC (IC₅₀ = 8 μM), MLCK (IC₅₀ = 12 μM). In RBL-2H3 cells, the selective inhibition of Syk by piceatannol results in inhibition of FceR1-mediated signaling. Also inhibits wheat embryo Ca²⁺-dependent protein kinase (CDPK) (IC₅₀ = 19 μM), and p72^syk (IC₅₀ = 10 μM), a non-receptor tyrosine kinase, relative to Lyn in isolated enzyme preparations. Also possesses anti-leukemic properties. Reported to activate sirtuins and promote the survival of eukaryotic cells.

생물학적 활성

Anti-inflammatory, immunomodulatory and antiproliferative agent. Inhibits p56 lck and syk protein tyrosine kinases and inhibits TNF-induced NF- κ B activation and gene expression. Synthesis results from conversion of resveratrol (5-[(1E)-2-(4-Hydroxyphenyl)ethenyl]-1,3,benzenediol ) by cytochrome P450 1B1.

PICEATANNOL 준비 용품 및 원자재

원자재

Benzene, 4-[(1E)-2-[3,5-bis(phenylmethoxy)phenyl]ethenyl]-1,2-bis(phenylmethoxy)- (E)-3,3',4,5'-TETRAMETHOXYSTILBENE 5-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenol 레스베라트롤 4-[(E)-2-(3,5-dimethoxyphenyl)ethenyl]-2-methoxy-phenol

준비 용품

PICEATANNOL 공급 업체

글로벌( 349)공급 업체

공급자	전화	이메일	국가	제품 수	이점
XI'AN TIANGUANGYUAN BIOTECH CO., LTD.	+86-029-86333380 18829239519	sales06@tgybio.com	China	959	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
BINBO BIOLOGICAL CO.,LTD	+8618629063126	info@binbobiological.com	China	290	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shanghai Zheyan Biotech Co., Ltd.	18017610038	zheyansh@163.com	CHINA	3620	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58
Chengdu GLP biotechnology Co Ltd	028-87075086 13350802083	scglp@glp-china.com	CHINA	1824	58

PICEATANNOL 관련 검색:

3,4',5-TRIMETHOXY-TRANS-STILBENE trans Resveratrol 3-O-β-D-Glucuronide Dihydroresveratrol CIS-TRIMETHOXY STILBENE Oxyresveratrol trans/cis Resveratrol-D4 Azo-Resveratrol cis Resveratrol trans Resveratrol 4O-b-D-Glucuronide 4'-Methoxyresveratrol Resveratrol 3,5-DIHYDROXY-4'-METHOXYSTILBENE 3-O-BETA-D-GLUCOSIDE Resveratrol-13C6 3,5-DIHYDROXY-4'-BROMOSTILBENE Acetyl-trans-resveratrol Resveratrol-3-4'-Disulfate Resveratrol 3-Sulfat-4’glucuronide 1-O-Levulinoyl Resveratrol Diacetate