E-4031
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E-4031 속성
- 저장 조건
- -20°C
- 용해도
- H2O: 용해성
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 회백색
- 안정성
- 흡습성
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
WGK 독일 | 3 |
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E-4031 C화학적 특성, 용도, 생산
용도
E-4031 has been used as:- human ether-a-go-go-related gene (hERG) blocker in human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs)
- IKr blocker in long QT syndrome (LQTS) induced pluripotent stem (iPSCs) embryoid bodies
- IKr blocker in rat ventricular myocytes
생물학적 활성
Selective blocker of hERG K + channels; inhibits the rapid delayed-rectifier K + current (I Kr ). Reversibly prolongs action potential duration in guinea pig papillary muscle and isolated ventricular myocytes, without affecting Na + or Ca 2+ inward currents. Class III antiarrhythmic agent.Biochem/physiol Actions
E-4031 is a antiarrhythmic drug and belongs to the class III type. It is a methanesulfonanilide compound and is effective in treating arrhythmia and modulates ventricular fibrillation. E-4031 mediates the prolongation of action potential duration (APD) in transgenic long-QT type 1 (LQT1) rabbits. An isoleucine mutation in human ether-a-go-go-related gene (hERG) abolishes its interaction with E-4031.E-4031 준비 용품 및 원자재
원자재
준비 용품
E-4031 공급 업체
글로벌( 78)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9354 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 |
sales@hzclap.com | CHINA | 6313 | 58 |
Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 |
support@targetmol.com | United States | 19973 | 58 |
LEAPCHEM CO., LTD. | +86-852-30606658 |
market18@leapchem.com | China | 43348 | 58 |
Amadis Chemical Company Limited | 571-89925085 |
sales@amadischem.com | China | 132020 | 58 |
J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 |
jkinfo@jkchemical.com | China | 96815 | 76 |
E-4031 관련 검색:
N-Methylbenzylamine
N,N-DIETHYL-N-[2-(2-PYRIDYL)ETHYL]AMINE
4-BENZOYLPIPERIDINE HYDROCHLORIDE
Betahistine dihydrochloride
N-(4-ACETYL-PHENYL)-METHANESULFON-AMIDE
E-4031,E-4031 DIHYDROCHLORIDE
4-(4-PIPERIDINYLMETHYL)-BENZENAMINE
4-(PHENYLMETHYL)-PIPERIDINE HYDROCHLORIDE
1-[2-(2-PYRIDYL)ETHYL]PIPERIDINE
E-4031
2-(2'-AMINOETHYL)-6-METHYLPYRIDINE
RARECHEM AL F1 4031
AURORA KA-4031
RARECHEM AK PP 4031
AKOS BB-4031
AURORA 4031
E-4031, Voltage-Gated (HERG) K+ Channel Blocker, 510.48MW