포란
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포란 속성
- 녹는점
- 48.5°C
- 끓는 점
- 48.5 °C
- 밀도
- 1.510 g/mL at 25 °C
- 증기압
- 238 mmHg ( 20 °C)
- 굴절률
- 1.3002
- 인화점
- 48-49°C
- 저장 조건
- 2-8°C
- 용해도
- 물에 거의 녹지 않으며, 에탄올 및 트리클로로에틸렌과 섞입니다.
- Specific Gravity
- approximate 1.50
- 색상
- 무색 내지 거의 무색
- 수용성
- 클로로포름과 에틸 아세테이트에 용해됩니다. 물에 섞이거나 혼합하기 어렵지 않습니다.
- Merck
- 14,5175
- BRN
- 1852087
- 안정성
- 안정적인.
- InChIKey
- PIWKPBJCKXDKJR-UHFFFAOYSA-N
- CAS 데이터베이스
- 26675-46-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,T,Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-67-48/20 | ||
안전지침서 | 26-36/37/39-24/25 | ||
유엔번호(UN No.) | UN 3334 | ||
WGK 독일 | 3 | ||
RTECS 번호 | KN6799000 | ||
위험 참고 사항 | Flammable/Toxic | ||
HS 번호 | 2909191800 | ||
유해 물질 데이터 | 26675-46-7(Hazardous Substances Data) | ||
독성 | An isomer of enflurane with similar anesthetic properties. Isoflurane has less effect on myocardial function, leaving the cardiovascular system normally responsive to epinephrine or hypercarbia, and it does not cause a marked increase in seizure susceptibility. It was not widely used because of reports that it caused increases in liver neoplasms in mice, but this observation has been challenged and the compound reintroduced. |
포란 C화학적 특성, 용도, 생산
화학적 성질
colourless liquid용도
Isoflurane is a halogenated ether used for inhalational anesthesia. Recent studies suggest that there might be a relationship between administration of isoflurane and postoperative cognitive dysfunct ion (POCD).Biological Functions
Isoflurane (Forane) is a structural isomer of enflurane and produces similar pharmacological properties: some analgesia, some neuromuscular blockade, and depressed respiration. In contrast, however, isoflurane is considered a particularly safe anesthetic in patients with ischemic heart disease, since cardiac output is maintained, the coronary arteries are dilated, and the myocardium does not appear to be sensitized to the effects of catecholamines. Also, blood pressure falls as a result of vasodilation, which preserves tissue blood flow. Isoflurane causes transient and mild tachycardia by direct sympathetic stimulation; this is particularly important in the management of patients with myocardial ischemia.Unlike enflurane, isoflurane does not produce a seizurelike EEG pattern. Furthermore, the metabolic transformation of isoflurane is only one-tenth that of enflurane, so fluoride production is quite low. Among the halogenated hydrocarbons, isoflurane is one of the most popular, since it preserves cardiovascular stability and causes a low incidence of untoward effects.
일반 설명
Isoflurane is a volatile liquid (bp=48.5°C) with an MAC of1.15, a blood:gas partition coefficient of 1.43 and high solubilityin fat. Isoflurane is a structural isomer of enflurane. Itis a known respiratory irritant, but less so than desflurane.Approximately 0.2% of the administered drug undergoesmetabolism, the rest is exhaled unchanged. The metabolismof isoflurane yields low levels of the nephrotoxic fluoride ionas well as a potentially hepatotoxic trifluoroacetylating compound). The relatively low concentrations ofthese compounds have resulted in very low risks of hepatotoxicityand nephrotoxicity. There have been no reports ofseizures caused by isoflurane and only transient increases inheart rate have been reported.Clinical Use
Isoflurane was introduced in the United States in 1981 and is a potent anesthetic agent with many similarities to its isomer enflurane (potent, nonflammable, and intermediate blood solubility). It does produce significantly fewer cardiovascular effects than enflurane, however, and it can be used safely with epinephrine without as great a concern for arrhythmia production. Isoflurane has a more pungent odor than halothane and, thus, can cause irritation to the throat and respiratory tract, triggering coughing and laryngospasm. To overcome this problem, it often is supplemented with intravenous agents. Less than 0.2% of an administered dose is metabolized, mostly to fluoride and trifluoroacetic acid. Some minimal potential for hepatotoxicity is associated with a trifluoroacetyl halide metabolite.포란 준비 용품 및 원자재
원자재
2,2,2-TRIFLUOROETHYL METHYL ETHER
HYDROGEN FLUORIDE GAS
트리플루오로에탄올
비스(클로로메틸)에테르
안티몬 펜타염화물
1-CHLORO-2,5-DIMETHYL-4-NITROBENZENE2-CHLORO-5-NITRO-P-XYLENE
hydrogen fluoride
불산
Methanol, difluoro- (6CI,8CI,9CI)
DIFLUOROMETHYL 2,2,2-TRIFLUOROETHYL ETHER
2,2-디클로로-1,1,1-트리플루오르에탄
1,1-DICHLORO-2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER
준비 용품
포란 공급 업체
글로벌( 240)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Jinan Shengqi pharmaceutical Co,Ltd | 86+18663751872 |
christine@shengqipharm.com | CHINA | 491 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10326 | 58 |