ChemicalBook
Chinese English Japanese Germany Korea

CAPREOMYCIN

CAPREOMYCIN 구조식 이미지
카스 번호:
11003-38-6
상품명:
CAPREOMYCIN
동의어(영문):
capastat;capromycin;capostatin;kapreomycin;CAPREOMYCIN;CAPREOMYCINE;CaproMycin, Caprolin, Capastat, Capostatin, L 29275
CBNumber:
CB8471646
분자식:
C50H88N28O15
포뮬러 무게:
1321.41232
MOL 파일:
11003-38-6.mol

CAPREOMYCIN 속성

산도 계수 (pKa)
pKa in 66% aq DMF: 6.2, 8.2, 10.1, 13.3(at 25℃)

안전

CAPREOMYCIN C화학적 특성, 용도, 생산

용도

Capreomycin is a complex of cyclic pentopeptides isolated from Streptomyces capreolus, first reported in 1962. The complex has two major components, IA and IB, with an exocyclic lysine residue and two minor delysinyl components, IIA and IIB. Capreomycin is a potent antibiotic with activity against mycobateria, Gram positive and Gram negative organisms. Capreomycin acts by binding to the 23S ribosomal subunit, disrupting protein synthesis.

Indications

Capreomycin (Capastat) is a polypeptide antibiotic derived from Streptomyces capreolus. It is bacteriostatic against most strains of M. tuberculosis, including the MDR strain. In addition, it is active against M. kansasii, M. avium, and in high concentrations, some grampositive and gram-negative bacteria. Like other antitubercular drugs, resistance to capreomycin occurs rapidly if the drug is used alone.There is no cross-resistance between streptomycin and capreomycin, but some isolates resistant to capreomycin are resistant to viomycin.

상표명

Capastat Sulfate (Lilly).

Pharmacology

Capreomycin is poorly absorbed from GI tract and so must be given parenterally. It is excreted mainly unchanged in the urine following glomerular filtration. Capreomycin is a used as a second-line agent in combination with other drugs. It appears to be particularly useful in multidrug regimens for the treatment of drugresistant tuberculosis, especially with streptomycin resistance. Capreomycin is associated with ototoxicity and nephrotoxicity, and these adverse effects can be severe in patients with preexisting renal insufficiency.

CAPREOMYCIN 준비 용품 및 원자재

원자재

준비 용품


CAPREOMYCIN 공급 업체

글로벌( 51)공급 업체
공급자 전화 팩스 이메일 국가 제품 수 이점
Xiamen AmoyChem Co., Ltd
+86 592-605 1114
sales@amoychem.com CHINA 6372 58
Chongqing Chemdad Co., Ltd
+86-13650506873
sales@chemdad.com CHINA 35438 58
career henan chemical co
0086-371-86658258
0086-371-86658258 factory@coreychem.com CHINA 29612 58
Suizhou HongQi Chemical Corporation Limited 0722-3257386,3257376,3257337,3257313
0722-3257381 2582618620@qq.com China 66 55
BOC Sciences
info@bocsci.com United States 10506 65
ChemStrong Scientific Co.,Ltd 15920483169 0755-66853366-
sales@chem-strong.com China 15617 56
Hunan HuaTeng Pharmaceutical Co., Ltd., 13319519070 400-859-2883
0731-82251112-818 viola@huatengsci.com China 6483 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169-
021-64609160 kewelchemexp@yahoo.com China 9807 50
Hangzhou J&H Chemical Co., Ltd.
0571-87396431 sales@jhechem.com; China 13904 53
Hubei Jusheng Technology Co.,Ltd 18871490274 027-59599241-
FAX:1400878000 sales@hubeijusheng.com;sales@hubeijusheng.com China 9865 58

Copyright 2019 © ChemicalBook. All rights reserved