ChemicalBook >제품 카탈로그 >SR 12813

SR 12813

SR 12813 구조식 이미지

카스 번호:: 126411-39-0

상품명:: SR 12813

동의어(영문):: GW485801;GW 485801;GW-485801;SR12813;SR 12813;SR-12813(GW 485801);SR-12813;SR12813;SR 12813;GW 485801;GW-485801;GW485801;GW-485801,GW485801,HMG-CoA Reductase (HMGCR),Autophagy,SR12813,inhibit,Inhibitor;Tetraethyl (2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl)bis(phosphonate);[[3,5-Bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-phosphonicacidtetraethylester;Phosphonic acid, P,P'-[[3,5-bis(1,1-dimethylethyl)-4-hydroxyphenyl]ethenylidene]bis-, P,P,P',P'-tetraethyl ester

CBNumber:: CB8497376

분자식:: C24H42O7P2

포뮬러 무게:: 504.53

MOL 파일:: 126411-39-0.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 56

SR 12813 속성

녹는점: 119-121℃

끓는 점: 552.6±50.0 °C(Predicted)

밀도: 1.117±0.06 g/cm3(Predicted)

저장 조건: Sealed in dry,Room Temperature

용해도: DMSO: ≥10 mg/mL

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 9.95±0.70(Predicted)

안전

WGK 독일	3
HS 번호	29319090

SR 12813 C화학적 특성, 용도, 생산

용도

SR 12813 is a pregnane X receptor (PXR, NR 112) agonist.

정의

ChEBI: An organic phosphonate that is the tetraethyl ester of [2-(3,5-di-tert-butyl-4-hydroxyphenyl)ethene-1,1-diyl]bis(phosphonic acid).

생물학적 활성

Pregnane X receptor (PXR) agonist (EC 50 values are 200 and 700 nM for human and rabbit PXR respectively). Activates the farnesoid X receptor (FXR) at μ M concentrations. Displays hypocholesterolaemic activity via enchanced degradation of HMG-CoA reductase.

SR 12813 준비 용품 및 원자재

원자재

준비 용품

SR 12813 공급 업체

글로벌( 56)공급 업체

공급자	전화	이메일	국가	제품 수	이점
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Dalian Meilun Biotech Co., Ltd.	0411-62910999 13889544652	sales@meilune.com	China	4647	58
Guangzhou Isun Pharmaceutical Co., Ltd	020-39119399 18927568969	isunpharm@qq.com	China	4428	55

SR 12813 관련 검색:

메틸렌디포스폰산 Benzoic acid, 4,5-difluoro-2-[[[6-(1H-imidazol-1-yl)-3-pyridazinyl]carbonyl]amino]- N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-2,3-dihydro-1,4-benzodioxin-2-carboxamide SR9009 SR-9243 SR9011 N-((4,5-difluoro-1H-benzo[d]imidazol-2-yl)methyl)-9-(3-fluorophenyl)-2-morpholino-9H-purin-6-amine TETRAETHYL METHYLENEDIPHOSPHONATE DIETHYL ALLYLPHOSPHONATE DIMETHYL VINYLPHOSPHONATE TETRAMETHYL METHYLENEDIPHOSPHONATE SR 12813 Tetraethyl vinylidene phosphonate, min. 97 % DIETHYL VINYLPHOSPHONATE