DMT-2′Fluoro-dU Phosphoramidite

DMT-2′Fluoro-dU Phosphoramidite 구조식 이미지
카스 번호:
146954-75-8
상품명:
DMT-2′Fluoro-dU Phosphoramidite
동의어(영문):
2‘-F-U amidite;2'-Fluoro-dU CEP;2’-F-dU Amidite;2’-F-rUPhosphoramidite;2'-F-U Phosphoramidite;2'-F-dU Phosphoramidite;5'-O-DMT-2'-fluoro-dU-CE;5'-O-DMT-2'-F-dU-3'-CEDPA;2'-Fluoro Uridine Amidite;DMT-2'-F-U Phosphoramidite
CBNumber:
CB8500324
분자식:
C39H46FN4O8P
포뮬러 무게:
748.78
MOL 파일:
146954-75-8.mol
MSDS 파일:
SDS

DMT-2′Fluoro-dU Phosphoramidite 속성

저장 조건
Sealed in dry,Store in freezer, under -20°C
물리적 상태
가루
산도 계수 (pKa)
9.39±0.10(Predicted)
색상
흰색에서 황백색까지
InChIKey
HQHQPAYRJJMYQX-YOKGOYKLNA-N
SMILES
N1(C=CC(=O)NC1=O)[C@@H]1O[C@H](COC(C2=CC=CC=C2)(C2C=CC(=CC=2)OC)C2=CC=C(C=C2)OC)[C@@H](OP(OCCC#N)N(C(C)C)C(C)C)[C@H]1F |&1:8,10,36,51,r|

안전

WGK 독일 3

DMT-2′Fluoro-dU Phosphoramidite C화학적 특성, 용도, 생산

정의

DMT-2′Fluoro-dU Phosphoramidite is also known as 2'-F-U CE-Phosphoramidite. 2'-F-RNA oligonucleotides adopt an A-form helix on hybridisation to a target. Whereas a hydroxyl group of RNA is a hydrogen bond donor, fluorine appears to be a weak acceptor. These features of 2'-F-RNA oligonucleotides lead to certain interesting properties. For example, it was demonstrated that oligonucleotides hybridise to a RNA oligonucleotide in the following order of increasing stability: DNA < RNA < 2'-OMe-RNA < 2'-F-RNA

DMT-2′Fluoro-dU Phosphoramidite 준비 용품 및 원자재

원자재

준비 용품


DMT-2′Fluoro-dU Phosphoramidite 공급 업체

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