4-Acetoxy-2-azetidinone
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4-Acetoxy-2-azetidinone 속성
- 녹는점
- 38-40 °C (lit.)
- 끓는 점
- 239.15°C (rough estimate)
- 밀도
- 1.3816 (rough estimate)
- 굴절률
- 1.4220 (estimate)
- 인화점
- >230 °F
- 저장 조건
- 2-8°C
- 용해도
- 포름산: 용해성50mg/mL, 투명, 노란색-주황색
- 산도 계수 (pKa)
- 13.41±0.40(Predicted)
- BRN
- 1524738
- CAS 데이터베이스
- 28562-53-0(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 34-43 | ||
| 안전지침서 | 26-36/37/39-45 | ||
| 유엔번호(UN No.) | UN 1759 8/PG 2 | ||
| WGK 독일 | 3 | ||
| 위험 등급 | 8 | ||
| 포장분류 | III |
| 그림문자(GHS): |
 
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| 신호 어: | Danger | |||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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4-Acetoxy-2-azetidinone C화학적 특성, 용도, 생산
화학적 성질
White crystalline powder용도
4-Acetoxy-2-azetidinone was used in the synthesis of derivatized cyclopentenes in high regio- and diastereoselectivity. It was also used as a heterocyclic synthon for antibiotic and anti-inflammatory agents.Purification Methods
Dissolve it in CHCl3, dry (MgSO4) concentrate at 40o/70mm, or better at room temperature to avoid decomposition. Wash and stir the residual oil with hexane by decantation and discard the wash. Dry the oil at high vacuum when it should solidify, m 34o. It can be distilled at high vacuum, 80-82o/10-3mm, but this results in extensive losses. The purity can be checked by TLC using Merck Silica Gel F254 and eluting with EtOAc. The azetidinone has RF 0.38 (typical impurities have RF 0.67). The spots can be detected by the TDM spray. This is prepared from (A) 2.5g 4,4'-tetramethyldiaminodiphenylmethane (TDM) in 10mL AcOH and diluted with 50mL of H2O, (B) 5g KI in 100mL of H2O and (C) 0.3g ninhydrin in 10mL of AcOH and 90mL of H2O. The spray is prepared by mixing (A) and (B) with 1.5mL of (C) and stored in a brown bottle. [Clau et al. Justus Liebigs Ann Chem 539 1974, Michel et al. Org Synth 65 135 1987, Beilstein 21/12 V 4.]4-Acetoxy-2-azetidinone 준비 용품 및 원자재
원자재
2-Azetidinone, 4-(acetyloxy)-1-(4-methoxyphenyl)-
(S)-(-)-4-OXO-2-AZETIDINECARBOXYLIC ACID
4-OXOAZETIDINE-2-CARBOXYLIC ACID
2-Azetidinone
아세트산 나트륨
클로로설포닐이소시아네이트
초산비닐모노머
과산화아세트산
아세트산(빙초산)
준비 용품
4-Acetoxy-2-azetidinone 공급 업체
글로벌( 154)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 |
peter@yan-xi.com | China | 5993 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 |
sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 |
eric@witopchemical.com | China | 23556 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9923 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | CHINA | 52867 | 58 |
4-Acetoxy-2-azetidinone 관련 검색:
(3R(1'R,4R))-(+)-4-아세톡시-3-(1-(T-뷰틸다이메틸실릴옥시)ETH)-2- 아제티디논
2-Azetidinone
Acetoxyacetyl chloride
Sodium triacetoxyborohydride
SILICON TETRAACETATE
Acetoxyacetic acid
4-BROMOMETHYLBIPHENYL
4-Aminopyrimidine
4-BroMo-3-Methyl-7-azaindole
4-Bromoindole
(3R,4R)-4-ACETOXY-3-[(3R)-1-(BUTYLDIMETHYL-SILYOXY)-ETHYL]-2-AZETIDIONE
Cyclobutanone
4-BENZOYLOXY-2-AZETIDINONE
Acetoxy
4-Acetoxy-2-azetidinone