메틸이소부틸케톤
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메틸이소부틸케톤 속성
- 녹는점
- -80 °C (lit.)
- 끓는 점
- 117-118 °C
- 밀도
- 0.801 g/mL at 25 °C (lit.)
- 증기 밀도
- 3.5 (vs air)
- 증기압
- 15 mm Hg ( 20 °C)
- 굴절률
- n
20/D 1.395(lit.)
- 인화점
- 56 °F
- 저장 조건
- Store at +5°C to +30°C.
- 용해도
- 물: 가용성20g/L
- 물리적 상태
- 액체
- 색상
- APHA: ≤15
- 냄새
- 즐거운; 온화하고 특징적이다. 날카로운; 비잔류; 케톤.
- Odor Threshold
- 0.17ppm
- 폭발한계
- 1.2-8%, 93°F
- ?? ??
- 녹색
- 수용성
- 17g/L(20℃)
- 최대 파장(λmax)
- λ: 335 nm Amax: 1.00
λ: 340 nm Amax: 0.50
λ: 360 nm Amax: 0.15
λ: 380 nm Amax: 0.02
λ: 400 nm Amax: 0.01
- JECFA Number
- 301
- Merck
- 14,5207
- BRN
- 605399
- Henry's Law Constant
- 2.56 at 25 °C (batch stripping method-GC, Kim et al., 2000)
- 노출 한도
- TLV-TWA 205 mg/m3 (50 ppm); STEL 300 mg/m3 (75 ppm) (ACGIH); IDLH 3000 ppm (NIOSH).
- Dielectric constant
- 13.0(Ambient)
- 안정성
- 휘발성 물질
- LogP
- 1.3-1.9 at 20℃
- CAS 데이터베이스
- 108-10-1(CAS DataBase Reference)
- IARC
- 2B (Vol. 101) 2013
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | F,Xn,T | ||
---|---|---|---|
위험 카페고리 넘버 | 11-20-36/37-66-39/23/24/25-23/24/25 | ||
안전지침서 | 9-16-29-45-36/37-7 | ||
유엔번호(UN No.) | UN 1245 3/PG 2 | ||
WGK 독일 | 1 | ||
RTECS 번호 | SA9275000 | ||
자연 발화 온도 | 840 °F | ||
TSCA | Yes | ||
HS 번호 | 2914 13 00 | ||
위험 등급 | 3 | ||
포장분류 | II | ||
유해 물질 데이터 | 108-10-1(Hazardous Substances Data) | ||
독성 | LD50 orally in rats: 2.08 g/kg (Smyth) | ||
IDLA | 500 ppm | ||
기존화학 물질 | KE-24725 |
메틸이소부틸케톤 C화학적 특성, 용도, 생산
용도
니트로 셀룰로오스, 잇몸, 옻칠 및 사용 우라늄 회수 용제로 사용됩니다. MIBK는 또한 제약 및 전기 도금 산업에 사용됩니다. 이러한 어플리케이션 외에도 새로운 반도체 산업이 출원되었습니다.포장, 보관 및 운송
드럼 및 용기는 발화원 및 열원이없는 통풍이 잘되는 곳에 보관해야합니다. 보관 온도는 40 ° C를 넘지 않아야합니다.개요
4-Methyl-2-pentanone has a pleasant odor. May be prepared by hydrogenation of mesityl oxide over Ni at 160 - 190°C; also by oxidation of methyl isobutyl carbinol.화학적 성질
4-Methyl-2-pentanone has a fruity, ethereal, spicy (on dilution) odor.물리적 성질
Clear, colorless, watery liquid with a mild, pleasant odor. Odor threshold concentration is 47 ppbv (Leonardos et al., 1969). Experimentally determined detection and recognition odor threshold concentrations were 400 μg/m3 (100 ppbv) and 1.1 mg/m3 (270 ppbv), respectively (Hellman and Small, 1974).출처
Reported found in orange and lemon juice, grape; vinegar, baked potato, papaya, ginger, wheat bread, cheeses, milk, cooked egg, roast chicken, cooked beef, lamb fat, pork liver, hop oil, beer, cognac, coffee, tea, plumcot, plum brandy, mushroom, trassi, sesame seed, buckwheat, wort, elder flower, Bourbon vanilla, clary and red sage, crab, clam and Chinese quince.용도
Methyl isobutyl ketone (hexone, isobutyl methyl ketone, 4-methyl-2-pentanone) is an organic solvent similar in structure and use to methyl butyl ketone. In addition to its use as a solvent for paints, lacquers, and varnishes, methyl isobutyl ketone is used in extraction processes and as a denaturant for rubbing alcohol. Methyl isobutyl ketone is also used as a synthetic flavoring in some varieties of rum, candy, and cheese. Unlike methyl butyl ketone, methyl isobutyl ketone has not been found to occur naturally.생산 방법
Methyl isobutyl ketone can be manufactured by two processes . The first is a mixed ketone process where MiBK, diisobutyl ketone, and acetone are coproduced in a single reaction using isopropanol as a starting material. The second method is used to produce the majority of MiBK and involves a three-step reaction sequence in which diacetone alcohol and mesityl oxide are formed as intermediates.제조 방법
By hydrogenation of mesityl oxide over Ni at 160 to 190°C; also by oxidation of methyl isobutyl carbinol.일반 설명
A clear colorless liquid with a pleasant odor. Flash point 73°F. Less dense than water. Vapors heavier than air.공기와 물의 반응
Highly flammable. 4-Methyl-2-pentanone is sensitive to air (may form explosive peroxides). Slightly soluble in water.반응 프로필
4-Methyl-2-pentanone is incompatible with caustic soda and other strong alkalis, hydrochloric acid, sulfuric acid and other strong inorganic acids, amines and oxidizing agents such as hydrogen peroxide, nitric acid, perchloric acid and chromium trioxide. 4-Methyl-2-pentanone reacts violently with potassium tert-butoxide. 4-Methyl-2-pentanone reacts vigorously with reducing materials. .위험도
Flammable, dangerous fire risk, explosivelimits in air 1.4–7.5%. Avoid ingestion and inhala-tion. Upper respiratory tract irritant, dizziness, andheadache. Possible carcinogen.건강위험
Vapor causes irritation of eyes and nose; high concentrations cause anesthesia and depression. Liquid dries out skin and may cause dermatitis; irritates eyes but does not injure them.화학 반응
Reactivity with Water No reaction; Reactivity with Common Materials: No reaction; Stability During Transport: Stable; Neutralizing Agents for Acids and Caustics: Not pertinent; Polymerization: Not pertinent; Inhibitor of Polymerization: Not pertinent.잠재적 노출
MIBK is used as a solvent; a denaturant; and as an extractant; in the manufacture of methyl amyl alcohol; as a solvent in paints, varnishes, and lacquers; as an alcohol denaturant; as a solvent in uranium extraction from fission products.Carcinogenicity
The National Toxicology Program conducted cancer bioassays by exposing groups of 50 male and 50 female F344 rats and B6C3F1 mice to MiBK vapor at 0, 450, 900, or 1800 ppm 6h/day, 5 days/ week for 2 years. Survival and body weight gain were decreased in male rats at 1800 ppm. Body weight gain was also decreased in male rats at 900 and in female mice at 1800ppm. A higher incidence of mineralization of the renal papilla was observed in male rats at all MiBK exposure levels. Chronic progressive nephropathy (CPN) and the incidences of adenoma and adenoma or carcinoma (combined) were increased for the male 1800 ppm exposure group. The severity of CPN and renal tubular hyperplasia was increased in all male rat exposure groups. An uncertain increase in mononuclear cell leukemia, adrenal medulla hyperplasia, and a positive trend for increases in benign or malignant pheochromocytomas (combined) were reported for the 1800 ppm male group. The NTP considered that there was some evidence of carcinogenic activity in male rats based on increased incidences of renal tubule neoplasms.None of the rodent bioassay results were considered clear evidence of carcinogenicity by NTP.
운송 방법
UN1245 Methyl isobutyl ketone, Hazard Class: 3; Labels: 3-Flammable liquid.Purification Methods
Reflux the ketone with a little KMnO4, wash it with aqueous NaHCO3, dry with CaSO4 and distil it. Acidic impurities are removed by passage through a small column of activated alumina. [Beilstein 1 IV 3305.]비 호환성
Able to form unstable and explosive peroxides on contact with air. Reacts violently with strong oxidizers, potassium tert-butoxide; strong acids; aliphatic amines; reducing agents폐기물 처리
Consult with environmental regulatory agencies for guidance on acceptable disposal practices. Generators of waste containing this contaminant (≥100 kg/mo) must conform to EPA regulations governing storage, transportation, treatment, and waste disposal. Incineration.메틸이소부틸케톤 준비 용품 및 원자재
원자재
준비 용품
3,5-다이메틸-1-헥신-3-올
프로피콘아졸
2,3,6-Trimethylphenol
(1,3-DIMETHYL-BUTYL)-HYDRAZINE
Fosinopril
Oxatomide
N-(1,3-다이메틸뷰틸-N'-페닐-p-페닐렌디아민)
2,2' 아조디2,4-디메틸-4-메톡시발레로니트리
이미벤코나졸
제스토덴
나이오븀 산화물(니오브 산화물)
라니티딘
4,5-DIAMINO-6-METHYLPYRIMIDINE
(1H-INDAZOL-3-YL)-ACETIC ACID
카테콜
Loperamide
1-(3,4-Dichlorophenyl)piperazine
2-(MORPHOLINE-4-CARBONYL)-BENZOIC ACID
Milrinone
Domperidone
칼륨 헵타플루오로탄탈산염
메틸이소부틸케톤 공급 업체
글로벌( 945)공급 업체
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PT CHEM GROUP LIMITED | +86-85511178 +86-85511178 |
peter68@ptchemgroup.com | China | 35453 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2966 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shandong chuangyingchemical Co., Ltd. | 18853181302 |
sale@chuangyingchem.com | CHINA | 5909 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |