디부틸 세바케이트

디부틸 세바케이트
디부틸 세바케이트 구조식 이미지
카스 번호:
109-43-3
한글명:
디부틸 세바케이트
동의어(한글):
디부틸세바신산염;디부틸세바케이트;디뷰틸세바신산염;디부틸세바신산;N-부틸세바신산;데칸디오산,디부틸에스테르;디-N-부틸세바신산;다이부틸세바케이트;디뷰틸세바신산염;디부틸 세바카테
상품명:
Dibutyl sebacate
동의어(영문):
PARAROSANILINE;MAGENTA;MAGENTA O;PARAFUCHSIN HYDROCHLORIDE;BASIC FUCHSIN HYDROCHLORIDE;Dibutyl Sebacate (1 mL) (AS);RUBIN;px404;ROSEIN;PX 404
CBNumber:
CB8737502
분자식:
C18H34O4
포뮬러 무게:
314.46
MOL 파일:
109-43-3.mol
MSDS 파일:
SDS

디부틸 세바케이트 속성

녹는점
205 °C (dec.)(lit.)
끓는 점
178-179 °C3 mm Hg(lit.)
밀도
0.94
증기압
0.001Pa at 25℃
굴절률
n20/D 1.441(lit.)
FEMA
2373 | DIBUTYL SEBACATE
인화점
>230 °F
저장 조건
Sealed in dry,Room Temperature
용해도
헥산, 톨루엔, 에탄올 및 아세톤: 가용성
물리적 상태
액체
Specific Gravity
0.937 (20/4℃)
색상
투명한
냄새
100.00%에서. 희미한 과일향, 기름진
?? ??
과일 같은
수용성
50mg/L(온도는 명시되지 않음)
JECFA Number
625
BRN
1798308
Dielectric constant
4.5(30℃)
LogP
6.30
CAS 데이터베이스
109-43-3(CAS DataBase Reference)
NIST
Di-n-butyl sebacate(109-43-3)
EPA
Dibutyl sebacate (109-43-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,Xi
위험 카페고리 넘버 40-36/37/38
안전지침서 36/37-36-26
WGK 독일 3
RTECS 번호 VS1150000
TSCA Yes
HS 번호 29171390
유해 물질 데이터 109-43-3(Hazardous Substances Data)
독성 LD50 oral in rat: 14870mg/kg
기존화학 물질 KE-09410
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
0 0

디부틸 세바케이트 MSDS


Dibutyl sebacate

디부틸 세바케이트 C화학적 특성, 용도, 생산

화학적 성질

Dibutyl sebacate is a clear, colorless, oily liquid with a bland to slight butyl odor.

용도

Dibutyl sebacate (DBS) is a dibutyl ester of sebacic acid. Dibutyl sebacate can be used for plastics in use in the food packaging industry, in plastics used for medical devices, and for pharmaceutical applications. Dibutyl sebacate is also used as a desensitizer in Otto fuel II, a torpedo monopropellant.

제조 방법

By distillation of sebacic acid with butyl alcohol in the presence of concentrated HCl in benzene solution or by reacting butyl alcohol and sebacyl chloride

생산 방법

Dibutyl sebacate is manufactured by the esterification of n-butanol and sebacic acid in the presence of a suitable catalyst, and by the distillation of sebacic acid with n-butanol in the presence of concentrated acid.

일반 설명

Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Dibutyl sebacate is a commonly used plasticizer, which can be synthesized by the reaction of butyl alcohol and sebacyl chloride or by the distillation of sebacic acid with butyl alcohol in the presence of concentrated hydrochloric acid in benzene solution.

Pharmaceutical Applications

Dibutyl sebacate is used in oral pharmaceutical formulations as a plasticizer for film coatings on tablets, beads, and granules, at concentrations of 10–30% by weight of polymer. It is also used as a plasticizer in controlled-release tablets and microcapsule preparations.
Dibutyl sebacate is also used as a synthetic flavor and flavor adjuvant in food products;for example,up to 5ppm is used in ice cream and nonalcoholic beverages.

Safety Profile

Mddly toxic by ingestion. Experimental reproductive effects. Combustible liquid when exposed to heat or flame; can react with oxidzing materials. To fight fire, use CO2 position it emits acrid smoke and fumes. See also ESTERS and n-BUTYL. ALCOHOL.

Safety

Dibutyl sebacate is used in cosmetics, foods, and oral pharmaceutical formulations, and is generally regarded as a nontoxic and nonirritant material. Following oral administration, dibutyl sebacate is metabolized in the same way as fats. In humans, direct eye contact and prolonged or repeated contact with the skin may cause very mild irritation. Acute animal toxicity tests and long-term animal feeding studies have shown no serious adverse effects to be associated with orally administered dibutyl sebacate.
LD50 (rat, oral): 16g/kg

저장

Dibutyl sebacate should be stored in a closed container in a cool, dry location. Dibutyl sebacate is stable under the recommended storage conditions and as used in specified applications under most conditions ofuse.Asanester,dibutylsebacatemayhydrolyzeinthe presence of water at high or low pH conditions.

비 호환성

Dibutyl sebacate is incompatible with strong oxidizing materials and strong alkalis.

Regulatory Status

Included in the FDA Inactive Ingredients Database (oral capsules, granules, film-coated, sustained action, and tablets). Included in the Canadian List of Acceptable Non-medicinal Ingredients.

디부틸 세바케이트 준비 용품 및 원자재

원자재

준비 용품


디부틸 세바케이트 공급 업체

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