NALBUPHINE HYDROCHLORIDE
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NALBUPHINE HYDROCHLORIDE 속성
- 인화점
- 9℃
- 저장 조건
- -20°C
- 용해도
- H2O: 용해성
안전
위험품 표기 | T+,T,F | ||
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위험 카페고리 넘버 | 26/27/28-39/23/24/25-23/24/25-11 | ||
안전지침서 | 22-36/37/39-45-36/37-16 | ||
유엔번호(UN No.) | 1544 | ||
WGK 독일 | 3 | ||
RTECS 번호 | QD3181000 | ||
위험 등급 | 6.1(a) | ||
포장분류 | II |
NALBUPHINE HYDROCHLORIDE C화학적 특성, 용도, 생산
용도
Nalbuphine is the free base form of Nalbuphine Hydrochloride. Nalbuphine is a mixed opioid agonist-antagonist. Nalbuphine is an analgesic (narcotic).원료
Nalbuphine is an antagonist at μ receptors and an agonist at κ receptors. As an antagonist, it has approximately one-fourth the potency of naloxone, and it produces withdrawal when given to addicts. On a weight basis, the analgesic potency of nalbuphine approaches that of morphine. An intramuscular injection of 10 mg will give about the same degree and duration of analgesia as an equivalent dose of morphine.Clinical Use
Nalbuphine is only available for parenteral dosage. Its elimination half-life is 2 to 3 hours. Metabolism of nalbuphine is by conjugation of the 3-OH group, and greater than 90% of the drug is excreted as conjugates in the feces.부작용
Side effects of nalbuphine are like those of other κ. Dysphoria is not as common as with pentazocine. Sedation is the most common side effect. Nalbuphine does not have the adverse cardiovascular properties found with pentazocine and butorphanol. Nalbuphine has low abuse potential and is not listed under the Controlled Substances Act.NALBUPHINE HYDROCHLORIDE 준비 용품 및 원자재
원자재
Cyclobutanecarbonyl chloride
수소화 리튬알미늄
nalbuphine
(5alpha)-4,5-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride
6-Keto Nalbuphine
7,8-Dihydro-14-hydroxy- normorphinone
준비 용품
NALBUPHINE HYDROCHLORIDE 관련 검색:
다이뷰틸아미노에탄올 하이드록시-1-메틸디페리딘
4-BUTYLPIPERIDINE
3-PIPERIDIN-3-YL-PROPAN-1-OL
BUTORPHANOL
1,2,3,4-TETRAHYDRO-2-NAPHTHOL
4-(METHOXYMETHYL)PIPERIDINE HCL
Cyclobutylmethylamine
8-DIMETHYLAMINO-1-OCTANOL
DIHYDROMORPHINE
(R)-3-PHENYLPROPANE-1,2-DIOL
(+)-(3R,4R)-3,4-DIMETHYL-4-(3-HYDROXYPHENYL)PIPERIDINE
(-)-NORMETAZOCINE >96% N-DEMETHYLATED AN ALOG
2,4-LUPETIDINE HCL
DIBUTYL-PHENETHYL-AMINE
NALBUPHINE HYDROCHLORIDE
1-(AMINOMETHYL)-CYCLOPROPANOL
1,2,3,4-TETRAHYDRO-NAPHTHALEN-2-YLAMINE HYDROCHLORIDE