아이소아밀 알코올
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아이소아밀 알코올 속성
- 녹는점
- -117 °C
- 끓는 점
- 131-132 °C
- 밀도
- 0.809 g/mL at 25 °C(lit.)
- 증기 밀도
- 3 (vs air)
- 증기압
- 2 mm Hg ( 20 °C)
- 굴절률
- n
20/D 1.407
- 인화점
- 109.4 °F
- 저장 조건
- room temp
- 용해도
- 25g/L
- 물리적 상태
- 액체
- 산도 계수 (pKa)
- >14 (Schwarzenbach et al., 1993)
- Specific Gravity
- 0.813 (15/4℃)
- 색상
- <20(APHA)
- pH 범위
- 5.6 at 25 g/l at 20 °C
- 냄새
- 약한 냄새, 무알콜
- 수소이온지수(pH)
- 7 (25g/l, H2O, 20℃)
- 폭발한계
- 1.2-9%, 100°F
- Odor Threshold
- 0.0017ppm
- ?? ??
- 발효된
- 수용성
- 25g/L(20℃)
- 최대 파장(λmax)
- λ: 260 nm Amax: 0.06
λ: 280 nm Amax: 0.06
- Merck
- 14,5195
- JECFA Number
- 52
- BRN
- 1718835
- Henry's Law Constant
- 33.1 at 37 °C (Bylaite et al., 2004)
- 노출 한도
- NIOSH REL: TWA 100 ppm (360 mg/m3), IDLH 500 ppm; OSHA PEL: TWA 100 ppm; ACGIH TLV: TWA 100 ppm, STEL 125 ppm (adopted).
- Dielectric constant
- 15.3(23℃)
- 안정성
- 안정적인. 가연성. 강산화제, 강산, 산 염화물, 산 무수물과 호환되지 않습니다.
- LogP
- 1.35 at 20℃
- CAS 데이터베이스
- 123-51-3(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn | ||
---|---|---|---|
위험 카페고리 넘버 | 10-20-37-66-20/22-R20/22-R10 | ||
안전지침서 | 46-16-S16 | ||
유엔번호(UN No.) | UN 1105 3/PG 3 | ||
WGK 독일 | 1 | ||
RTECS 번호 | EL5425000 | ||
자연 발화 온도 | 644 °F | ||
TSCA | Yes | ||
위험 등급 | 3 | ||
포장분류 | II | ||
HS 번호 | 29335995 | ||
유해 물질 데이터 | 123-51-3(Hazardous Substances Data) | ||
독성 | LD50 orally in rats: 7.07 ml/kg (Smyth) | ||
IDLA | 500 ppm | ||
기존화학 물질 | KE-23575 |
아이소아밀 알코올 C화학적 특성, 용도, 생산
화학적 성질
Isoamyl alcohol has a fusel oil, whiskey-characteristic, pungent odor and repulsive taste. The air odor threshold for 3-methyl-1-butanol was reported as 0.042 ppm , which provides some acute warning for exposure to this chemical.물리적 성질
Clear, colorless liquid with a pungent odor. An odor threshold concentration of 1.7 ppbv was reported by Nagata and Takeuchi (1990).출처
Constitutes the major portion of fusel oil; also known as fermentation of amyl alcohol; it has been identified as an ester among the constituents of Roman chamomile oil; French peppermint, Java citronella, Réunion geranium, tea, Teucrium chamaedrys, Eucalyptus amigdalina, Achillea ageratum and Artemisia camphorata. It is reported present in the aromas of strawberry and raspberry. It is also reported found in over 230 natural sources including apple, apricot, banana, sweet and sour cherry, citrus peel oils and juices, berries, guava, grapes, raisin, melon, papaya, peach, pear, pineapple, asparagus, cabbage, kohlrabi, celery stalk and seed, leek, peas, potato, sauerkraut, tomato, ginger, mint oils, vinegar, mustard, bread, cheeses, butter, milk, fish,meats, cognac, rum, whiskies, cider, sherry, grape wines, tea, filberts, pecans, walnuts, oats, honey, soybean, avocado, Arctic bramble, olive, passion fruit, rose and Malay apple, mushroom, mango, tamarind, pear brandy, port, cardamom, gin, quince, radish, sukiyaki, sake, buckwheat, corn oil, sweet corn, laurel, malt, wort, cherimoya, loquat, Bourbon vanilla, shrimp, oysters, crayfish, mussels and scallops용도
3-Methyl-1-butanol and 2-methyl-1-butanol are normally used as apple or banana flavoring agents for wine. They can also be used as chemical intermediates and solvents in pharmaceutical products.제조 방법
3-Methyl-1-butanol and 2-methyl-1-butanol were first isolated from fusel oils, by-products of ethanol fermentation by yeast. These compounds can also be derived from the chlorination of pentane followed by hydrolysis. Another alternative process is the oxo process, a general strategy for the manufacture of C4 and higher alcohols. Both the chlorination process and the oxo process are current commercial processes for the production of 3-methyl-1-butanol and 2-methyl-1-butanol, but the oxo process via the hydroformylation reaction is the more popular. Two main technologies are used for the process. The first was brought on stream by Ruhrchemie in Germany and Exxon in USA in the 1940s and is generally referred to as "high-pressure cobalt catalyst technology." The active catalyst species is cobalt hydrocarbonyl, and a pressure of 200–300 atm is required to maintain the stability of the catalyst. In the early 1960s, Shell commercialized a modern version of the cobalt catalyst process. This technology uses organophosphine ligands, which allows a lower operating pressure of 30–100 atm but at the expense of the catalyst activity. The Shell technology is employed primarily in the production of linear primary alcohols, whereas the high-pressure cobalt technology is frequently used in the production of branched alcohols.생산 방법
Isoamyl alcohol has a characteristic pungent odor and repulsive taste. Industrially prepared by rectification of fusel oil.정의
ChEBI: Isoamylol is an primary alcohol that is butan-1-ol in which a hydrogen at position 3 has been replaced by a methyl group. It has a role as a xenobiotic metabolite, a Saccharomyces cerevisiae metabolite and an antifungal agent. It is a primary alcohol, a volatile organic compound and an alkyl alcohol. It derives from a hydride of an isopentane.일반 설명
Colorless liquid with a mild, choking alcohol odor. Less dense than water, soluble in water. Hence floats on water. Produces an irritating vapor.공기와 물의 반응
Highly flammable. Water soluble.반응 프로필
3-Methyl-1-butanol attacks plastics [Handling Chemicals Safely, 1980. p. 236]. Mixtures with concentrated sulfuric acid and strong hydrogen peroxide may cause explosions. Mixing with hypochlorous acid in water or water/carbon tetrachloride solution can generate isoamyl hypochlorites, which may explode, particularly on exposure to sunlight or heat. Mixing with chlorine would also yield isoamyl hypochlorites [NFPA 491 M, 1991]. Base-catalysed reactions with isocyanates can occur with explosive violence [Wischmeyer,1969].위험도
Moderate fire risk. Vapor is toxic and irritant. Explosive limits in air 1.2–9%.건강위험
Very high vapor concentrations irritate eyes and upper respiratory tract. Continued contact with skin may cause irritation.잠재적 노출
(n-isomer); Suspected reprotoxic hazard, Primary irritant (w/o allergic reaction), (iso-, primary): Possible risk of forming tumors, Primary irritant (w/o allergic reaction), (sec-, active primary-, and other isomers) Primary irritant (w/o allergic reaction). Used as a solvent in organic synthesis and synthetic flavoring, pharmaceuticals, corrosion inhibitors; making plastics and other chemicals; as a flotation agent. The (n-isomer) is used in preparation of oil additives, plasticizers, synthetic lubricants, and as a solvent.환경귀착
Biological. Using the BOD technique to measure biodegradation, the mean 5-d BOD value (mM BOD/mM isoamyl alcohol) and ThOD were 4.46 and 59.5%, respectively (Vaishnav et al., 1987).Chemical/Physical. Isoamyl alcohol will not hydrolyze because it has no hydrolyzable functional group (Kollig, 1993).
운송 방법
UN2811 Pentanols, Hazard Class: 3; Labels: 3- Flammable liquid. UN1987 Alcohols, n.o.s., Hazard Class: 3; Labels: 3-Flammable liquid.Purification Methods
Dry the alcohol by heating with CaO and fractionally distilling, then heating with BaO and redistilling. Alternatively, boil it with concentrated KOH solution, wash it with dilute H3PO4, and dry it with K2CO3, then anhydrous CuSO4, before fractionally distilling it. If very dry alcohol is required, the distillate is refluxed with the appropriate alkyl phthalate or succinate as described for ethanol. It is separated from 2-methyl-1-butanol by fractional distillation, fractional crystallisation and preparative gas chromatography. [Beilstein 1 IV 1677.]비 호환성
Forms an explosive mixture with air. Contact with strong oxidizers and hydrogen trisulfide may cause fire and explosions. Incompatible with strong acids. Violent reaction with alkaline earth metals forming hydrogen, a flammable gas.폐기물 처리
Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.아이소아밀 알코올 준비 용품 및 원자재
원자재
준비 용품
이소밸러알데히드
부틸산이소아밀
Isopentyl phenylacetate
Diethyl isoamylmalonate
Lobenzarit
Ethopabate
노르플록사신
포름산이소아밀
아질산 아이소아밀
1,3-디시클로헥실우레아
Ethyl 2-(4-hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
Ethyl 2-(4-(ethoxycarbonyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
브롬발레릴 요소
피메리산
Ethyl 2-(4-(hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxylate
아이소펜틸 아세토아세테이트
브푸로페진
Diethyl ethyl(isoamyl)malonate
Calcitonin
피나콜린
(3-메톡시부톡시)아세트 산 2-프로페닐 에스테르; 2-프로페닐 (3-메틸부톡시)아세테이트
2-Bromo-3-methylbutanoyl bromide
아밀 살리실산염
2-(4-Hydroxypiperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide
GALLIC ACID ISOAMYL ESTER
벤조산이소아밀에스테르
Sodium isoamylxanthate
Isopentyl isobutyrate
FEMA 2080
2-(4-(Hydroxymethyl)piperidin-1-yl)-6-(trifluoromethyl)pyrimidine-4-carboxamide
N,N-Diethyl-4-nitrosoaniline
초산 이소아밀
이소길초산이소아밀
pinacolone,tert-butyl methy1 ketone,3,3-dimethyl-2-butyl ketone
1-(4-(Hydroxymethyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-ol
이소발레릴산
1,3-BENZODITHIOLYLIUM TETRAFLUOROBORATE
프로피온산이소아밀
(1-(4-(Hydroxymethyl)-6-(trifluoromethyl)pyrimidin-2-yl)piperidin-4-yl)methanol
이소아밀브로마이드
아이소아밀 알코올 공급 업체
글로벌( 571)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 |
kaia@neputrading.com | China | 1011 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
SHANDONG ZHI SHANG CHEMICAL CO.LTD | +86 18953170293 |
sales@sdzschem.com | China | 2931 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 |
info@longyupharma.com | China | 2531 | 58 |