2-Chloro-5-nitropyridine
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2-Chloro-5-nitropyridine 속성
- 녹는점
- 105-108 °C (lit.)
- 끓는 점
- 256.6±20.0 °C(Predicted)
- 밀도
- 1.6616 (rough estimate)
- 굴절률
- 1.5500 (estimate)
- 인화점
- 158°C
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 산도 계수 (pKa)
- -4.22±0.10(Predicted)
- 물리적 상태
- 결정성 분말
- 색상
- 밝은 노란색에서 베이지색까지
- 수용성
- 뜨거운 메탄올에 대한 용해도. 물에 불용성.
- BRN
- 120453
- InChI
- InChI=1S/C5H3ClN2O2/c6-5-2-1-4(3-7-5)8(9)10/h1-3H
- InChIKey
- BAZVFQBTJPBRTJ-UHFFFAOYSA-N
- SMILES
- C1(Cl)=NC=C([N+]([O-])=O)C=C1
- CAS 데이터베이스
- 4548-45-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38 | ||
| 안전지침서 | 26-36-37/39 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | US7175000 | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29333990 | ||
| 기존화학 물질 | KE-05792 |
2-Chloro-5-nitropyridine C화학적 특성, 용도, 생산
화학적 성질
white to light yellow crystal용도
2-Chloro-5-nitropyridine is used as a pharmaceutical intermediate.용도
2-chloro-5-nitropyridine is an important pyridine derivative and is an intermediate for synthesizing bactericides, plant growth regulators, antibiotics and other medicaments.Synthesis
Into a 500 ml four-necked flask equipped with a thermometer, stirring and reflux condenser, 50 g of phosphorus oxychloride, 14.0 g (0.1 mole) of 2-hydroxy-5-nitropyridine prepared in Example 1, 25.0 g (0.12 Mol) Phosphorus pentachloride,Stir and react at 100-105°C for 5 hours,Then the phosphorus oxychloride was recovered by distillation under reduced pressure, and the remainder was slowly poured into 120 grams of ice water, fully stirred, and then a 40wt% aqueous sodium hydroxide solution was neutralized to a pH of 8-9.Separate the layers, extract the aqueous layer with dichloromethane three times, 60 grams each time, combine the organic phases,Washed with 20 grams of saturated brine, then dried with 2.0 grams of anhydrous sodium sulfate, distilled to recover dichloromethane, and dried to obtain 15.1 grams of 2-chloro-5-nitropyridine (I), yield 95.3%, gas purity 99.8 %.Purification Methods
It crystallises from *benzene or *benzene/pet ether. [Beilstein 20/5 V 452.]2-Chloro-5-nitropyridine 준비 용품 및 원자재
원자재
2-아미노-5-나이트로피리딘
포스포러스옥시클로라이드
질산
2-아미노피리딘
2-히드록시-5-니트로피리딘
2-Amino-6-chloro-3-nitropyridine
2-Chloro-5-nitropyridin-4-amine
준비 용품
4-(5-Nitropyridin-2-yl)morpholine
5-Nitropyridine-2-carboxylic acid
1-[5-NITROPYRIDIN-2-YL]PIPERIDINE-4-OL
5-AMINO-2-METHOXY-ISONICOTINIC ACID
6-(1-PYRROLIDINYL)-3-PYRIDINAMINE
1-(5-aminopyridin-2-yl)piperidin-4-ol
3-Amino-6-morpholinopyridine
7-CHLORO-10-(4-HYDROXYANILINO)-2-METHOXY BENZO(B)-1,5-NAPHTHY RIDINE
5-NITRO-2-(1-PYRROLIDINYL)PYRIDINE
5-Amino-2-chloropyridine
5-Amino-2-methylpyridine
2-Methoxy-5-nitropyridine
3-아미노피리딘
5-Aminopyridine-2-carboxylic Acid
5-Amino-2-methoxypyridine
2-Chloro-5-nitropyridin-4-amine
NVP-LDE225
2-Methyl-5-nitropyridine
2-Chloro-5-nitropyridine 공급 업체
글로벌( 651)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shenyang TYSChem Co., Ltd. | +86-24-83607930 +8618640359690 |
sales@honghuchem.com | China | 403 | 58 |
| Terma Medicare India Pvt.,Ltd | +8613916485955 |
shivshanghai@yahoo.com | India | 132 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7786 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 951 | 58 |
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 885 | 50 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| China Synchem Technology Co.,Ltd. | +86-0552-4929304 +86-18055277008 |
wangxuhui1985@126.com | China | 55 | 55 |
2-Chloro-5-nitropyridine 관련 검색:
2-클로로-5-클로로메틸피리딘 펜타클로로피리딘 클로피돌 M-니트로클로로벤젠 클로로디플루오르메탄 P-클로로니트로벤젠 1-(클로로메틸)-4-니트로벤젠 O-클로로니트로벤젠 이산화질소
2-Chloro-3-cyanopyridine
6-Chloro-2-methyl-3-nitropyridine
2-Chloro-5-methylpyridine
5-Amino-2-chloropyridine
2-chloro-5-cyanopyridine
2-Chloro-5-fluoropyridine
3-Bromo-6-chloro-2-methylpyridine
5-Bromo-2-chloropyridine
2-Chloro-5-hydroxypyridine