3-아미노페놀

3-아미노페놀
3-아미노페놀 구조식 이미지
카스 번호:
591-27-5
한글명:
3-아미노페놀
동의어(한글):
3-아미노-1-히드록시벤젠;3-아미노페놀;M-아미노페놀
상품명:
3-Aminophenol
동의어(영문):
M-AMINOPHENOL;META AMINO PHENOL;m-Aminofenol;3-HYDROXYANILINE;1-Amino-3-hydroxybenzene;3-AMINO-1-HYDROXYBENZENE;nakoteg;renaleg;ursoleg;furroeg
CBNumber:
CB8853903
분자식:
C6H7NO
포뮬러 무게:
109.13
MOL 파일:
591-27-5.mol
MSDS 파일:
SDS

3-아미노페놀 속성

녹는점
120-124 °C (lit.)
끓는 점
164 °C/11 mmHg (lit.)
밀도
0.99
증기압
0.019Pa at 20℃
굴절률
1.5444 (estimate)
인화점
155 °C
저장 조건
2-8°C
용해도
26g/L
색상 색인 번호
76545
물리적 상태
결정성 분말
산도 계수 (pKa)
4.37, 9.82(at 20℃)
색상
흰색에서 분홍빛이 도는 밝은 회색
수소이온지수(pH)
6.8 (10g/l, H2O, 20℃)
냄새
냄새 없는
수용성
35g/L(20℃)
Merck
14,460
BRN
636059
안정성
안정적인. 타기 쉬운. 강한 산화제, 염기, 무기산과 호환되지 않습니다. 가볍거나 공기에 민감할 수 있습니다.
LogP
0.183 at 20℃
CAS 데이터베이스
591-27-5(CAS DataBase Reference)
NIST
Phenol, 3-amino-(591-27-5)
EPA
3-Aminophenol (591-27-5)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xn,N
위험 카페고리 넘버 20/22-51/53
안전지침서 28-61-28A
유엔번호(UN No.) UN 2512 6.1/PG 3
WGK 독일 2
RTECS 번호 SJ4900000
TSCA Yes
위험 등급 6.1
포장분류 III
HS 번호 29222900
유해 물질 데이터 591-27-5(Hazardous Substances Data)
독성 LD50 i.p. in mice: 4.5 mg/20g (Koelzer, Giesen)
기존화학 물질 KE-01528
그림문자(GHS): GHS hazard pictogramsGHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H411 장기적 영향에 의해 수생생물에 유독함 수생 환경유해성 물질 - 만성 구분 2
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P264 취급 후에는 손을 철저히 씻으시오.
P264 취급 후에는 손을 철저히 씻으시오.
P273 환경으로 배출하지 마시오.
P301+P312 삼켜서 불편함을 느끼면 의료기관(의사)의 진찰을 받으시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
0
2 0

3-아미노페놀 MSDS


3-Aminophenol

3-아미노페놀 C화학적 특성, 용도, 생산

화학적 성질

Light grey crystal powder

용도

3-Aminophenol is an aromatic compound used in the preparation of inhibitors of mammalian carbonic anhydrase isoforms. Also used in the preparation of quinoline tethered fluorescent carbon dots for regulated anticancer discovery.

주요 응용

3-Aminophenol has been used in the synthesis of disulfonated bis[4-(3-aminophenoxy)phenyl]sulfone (S-BAPS).
It can be used to synthesize:
Methyl 2-oxo-7-[(triphenylphosphoranylidene)amino]-2H-chromene-4-carboxylate by reacting with dimethyl acetylenedicarboxylate (DMAD) in the presence of triphenylphosphine.
3-Amino-2-cyclohexen-1-one via palladium-catalyzed hydrogenation.

정의

ChEBI: An aminophenol that is one of three amino derivatives of phenol which has the single amino substituent located meta to the phenolic -OH group.

일반 설명

White crystals or off-white flakes.

공기와 물의 반응

3-Aminophenol may be sensitive to prolonged exposure to air and light. Slightly soluble in water.

반응 프로필

3-Aminophenol may react with strong oxidizers and mineral acids or bases.

위험도

Toxic by ingestion.

화재위험

Flash point data for 3-Aminophenol are not available. 3-Aminophenol is probably combustible.

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. An experimental teratogen. Other experimental reproductive effects. Mutation data reported. A skin and eye irritant. When heated to decomposition it emits toxic fumes of NOx,.

잠재적 노출

Workers may be exposed to oAminophenol during its use as a chemical intermediate; in the manufacture of azo and sulfur dyes; and in the photographic industry. There is potential for consumer exposure to o-Aminophenol because of its use in dyeing hair, fur, and leather. The compound is a constituent of 75 registered cosmetic products suggesting the potential for widespread consumer exposure. p-Aminophenol is used mainly as a dye, dye intermediate and as a photographic developer; and in small quantities in analgesic drug preparation. Consumer exposure to p-aminophenol may occur from use as a hairdye or as a component in cosmetic preparations. mAminophenol is used mainly as a dye intermediate

운송 방법

UN2512 Aminophenols (o-; m-; p-), Hazard Class: 6.1; Labels: 6.1-Poisonous materials

Purification Methods

Crystallise it from hot water or toluene. [Beilstein 13 IV 952.]

비 호환성

These phenol/cresol materials can react with oxidizers; reaction may be violent. Incompatible with strong reducing substances such as alkali metals, hydrides, nitrides, and sulfides. Flammable gas (H2) may be generated, and the heat of the reaction may cause the gas to ignite and explode. Heat may be generated by the acidbase reaction with bases; such heating may initiate polymerization of the organic compound. Reacts with boranes, alkalies, aliphatic amines, amides, nitric acid, sulfuric acid. Phenols are sulfonated very readily (e.g., by concentrated sulfuric acid at room temperature). These reactions generate heat. Phenols are also nitrated very rapidly, even by dilute nitric acid and can explode when heated. Many phenols form metal salts that may be detonated by mild shock.

폐기물 처리

Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner and scrubber. All federal, state, and local environmental regulations must be observed.

3-아미노페놀 준비 용품 및 원자재

원자재

준비 용품


3-아미노페놀 공급 업체

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