Alarelin Acetate

Alarelin Acetate 구조식 이미지
카스 번호:
79561-22-1
상품명:
Alarelin Acetate
동의어(영문):
Alarelin Acetate;(DES-GLY10,D-ALA6,PRO-NHET9)-LUTEINIZING HORMONE-RELEASING FACTOR (SEA BREAM);ALARELIN;SURFAGON;Allah Lin;Alareline Acetate;Alarelin impurity;Alarelin USP/EP/BP;Alarelin DiAcetate;Alarelin acetate salt
CBNumber:
CB9119598
분자식:
C58H82N16O14
포뮬러 무게:
1227.39
MOL 파일:
79561-22-1.mol

Alarelin Acetate 속성

저장 조건
−20°C
용해도
≥128.7 mg/mL in DMSO; ≥128.6 mg/mL in EtOH; ≥128.8 mg/mL in H2O
물리적 상태
가루
시퀀스
Glu-His-Trp-Ser-Tyr-D-Ala-Leu-Arg-Pro-NHEt
InChIKey
IMRONVSKLHSCMF-VWCBMNBRNA-N
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 T
위험 카페고리 넘버 60
안전지침서 53-45
WGK 독일 3
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H360 태아 또는 생식능력에 손상을 일으킬 수 있음 생식독성 물질 구분 1A, 1B 위험 GHS hazard pictograms
예방조치문구:

Alarelin Acetate C화학적 특성, 용도, 생산

Cytotoxicity

Cell Assay
The cells are trypsinized in a solution of 2.5 g/L trypsin and seeded in a 96-well plate. After the cells are grown for 24 h to approximately 800 g/L subconfluent state, 0.1 mL medium containing 2.5% calf serum and various concentrations (0.001, 0.1, 10 μM) of alarelin is added to each well, respectively, and incubated for 24 h in a CO2 incubator. Each concentration is tested in at least 12 wells. Briefly, 15 μL of MTT solution is added to each well and incubated for 4 h. Then, the medium and MTT are removed and 150 μL of DMSO is added to each well and shaken for 10 min to dissolve the crystal. The OD is determined at 490 nm using an ELISA reader.
Animal Administration
Rats: Male Sprague-Dawley rats are divided into two groups. In Group I: Gastric acid secretion is measured in a chambered stomach. Briefly, the abdomen is incised, and both the stomach and duodemun are exposed and tied respectively; then 1.5 mL 0.9% sodium chloride (containing Alarelin, 2 μg/kg) is infused into the each chambered stomach. After 15, 30, 45, 60 min, the gastric juice is drew out of the chambered stomach and the pH is measured in the ABL-500 respectively. The control is infused saline instead of Alarelin. In Group II: After anaesthetized, 2 mL Alarelin (2 μg/kg) is administered into the tail vein. The control is injected the saline instead of Alarelin. Then, the stomach and duodenum are tied and infused 1.5 mL saline immediately. After 15, 30, 45, 60 min, the gastric juice is also drew out of the chambered stomach and the pH is measured in the ABL-500 respectively.

Alarelin Acetate 준비 용품 및 원자재

원자재

준비 용품


Alarelin Acetate 공급 업체

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Alpha Biopharmaceuticals Co., Ltd
+86-411-39042497 +8613921981412
sales@alphabiopharm.com China 886 58
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+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21691 55

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