4-(Iodomethyl)tetrahydro-2H-pyran
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4-(Iodomethyl)tetrahydro-2H-pyran 속성
- 끓는 점
- 229.1±13.0 °C(Predicted)
- 밀도
- 1.645±0.06 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Store in freezer, under -20°C
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험 카페고리 넘버 | 34 | ||
|---|---|---|---|
| 안전지침서 | 23-26-36/37/39-45 |
4-(Iodomethyl)tetrahydro-2H-pyran C화학적 특성, 용도, 생산
Synthesis
4-(Iodomethyl)tetrahydro-2H-pyran is prepared from 4-(methanesulfonyloxymethyl)tetrahydropyran by heating and refluxing under conditions of reaction with sodium iodide in acetone. The specific method of operation is described below: .Preparation: A mixture of Preparation (328g, 1.69mol) and sodium iodide (507g, 3.4mol) in acetone (3.3L) was refluxed for 4h. TLC (diethyl ether) showed significant mesylate remaining so further sodium iodide (127g, 0.65mol) was added and reflux continued for 16h. The mixture was cooled and filtered. The resulting cake was washed with acetone, dried, and11then partitioned between diethyl ether (800mL) and water (800mL). The aqueous phase was re-extracted with diethyl ether (200mL), the ether extracts combined and washed with 10% sodium thiosulphate solution (300mL) which decolourised the extract. Final washing with water (300mL), drying (MgS04) and then removal of the solvent provided the 4-(IODOMETHYL)TETRAHYDRO-2H-PYRAN (365g, 92% yield).
4-(Iodomethyl)tetrahydro-2H-pyran 준비 용품 및 원자재
원자재
Tetrahydropyran-4-ylmethyl methanesulfonate
(TETRAHYDRO-2H-PYRAN-4-YL)METHANOL
(Tetrahydro-2H-pyran-4-yl)methyl 4-methylbenzenesulphonate
준비 용품
4-(Iodomethyl)tetrahydro-2H-pyran 공급 업체
글로벌( 107)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 |
shangli@bocchem.com | China | 138 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 |
joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Alfa Chemistry | |
info@alfa-chemistry.com | United States | 2344 | 58 |
| Aston Chemical | 13000000000 |
sales@astonchem.com | United States | 1634 | 58 |
| Hefei Hirisun Pharmatech Co., Ltd | +8615056975894 |
shawn@hirisunpharm.com | CHINA | 9923 | 58 |