HEMATOPORPHYRIN

HEMATOPORPHYRIN C화학적 특성, 용도, 생산

용도

Hematoporphyrin (Photodyn, Sensibion) is a porphyrin prepared from hemin. It is a derivative of protoporphyrin IX, where the two vinyl groups have been hydrated (coverted to alcohols). It is used as a photosensitizer in photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy. Hematoporphyrin has also been used as an antidepressant and antipsychotic since the 1920s.

정의

ChEBI: A dicarboxylic acid that is protoporphyrin in which the vinyl groups at positions 7 and 12 are replaced by 1-hydroxyethyl groups.

위험도

Toxic. Reported to be preferentially absorbed by cancerous tissues, making them fluoresce under UV light.

Purification Methods

Purify it by dissolving it in EtOH Hematoporphyrin and adding H2O or Et2O to give deep red crystals. It has also been recrystallised from MeOH. UV has max at 615.5, 565, 534.4 and 499.5nm in 0.1N NaOH, and 597, 619, 634, 653, 683 and 701nm in 2N HCl [Falk Porphyrins and Metalloporphyrins Elsevier, NY, p 175 1964, LCCCNo 63-19821.] It is used in the affinity chromatographic purification of Heme proteins [Olsen Methods Enzymol 123 324 1986]. The O-methyl-dimethyl ester has m 203-206o (from CHCl3/MeOH), and the O,O'-dimethyl-dimethyl ester has m 145o (from CHCl3/MeOH). [Paul Acta Chem Scand 5 389 1951, Beilstein 26 III/IV 3157, and 3158 for the HCl.]

HEMATOPORPHYRIN 준비 용품 및 원자재

원자재

준비 용품

HEMATOPORPHYRIN 공급 업체

공급자	전화	이메일	국가	제품 수	이점
airuikechemical co., ltd.	+undefined86-15315557071	sales02@airuikechemical.com	China	994	58
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9350	55
Xiamen AmoyChem Co., Ltd	+86-592-6051114 +8618959220845	sales@amoychem.com	China	6387	58
career henan chemical co	+86-0371-86658258 15093356674;	factory@coreychem.com	China	29826	58
Zhengzhou Alfa Chemical Co.,Ltd	+8618530059196	sale04@alfachem.cn	China	12478	58
SIMAGCHEM CORP	+86-13806087780	sale@simagchem.com	China	17367	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
WinWin Chemical CO., Limited	+86-0086-577-64498589 +86-15355981851	sales@win-winchemical.com	China	13854	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29321	58
AFINE CHEMICALS LIMITED	0571-85134551	info@afinechem.com	CHINA	15377	58

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