3-Fluoro-4-nitrobenzoic acid
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3-Fluoro-4-nitrobenzoic acid 속성
- 녹는점
- 174-175°C
- 끓는 점
- 372.8±27.0 °C(Predicted)
- 밀도
- 1.568±0.06 g/cm3(Predicted)
- 저장 조건
- Sealed in dry,Room Temperature
- 용해도
- 메탄올에 용해됨
- 물리적 상태
- powder to crystal
- 산도 계수 (pKa)
- 3.08±0.10(Predicted)
- 색상
- White to Light yellow to Green
- InChI
- InChI=1S/C7H4FNO4/c8-5-3-4(7(10)11)1-2-6(5)9(12)13/h1-3H,(H,10,11)
- InChIKey
- WVZBIQSKLXJFNX-UHFFFAOYSA-N
- SMILES
- C(O)(=O)C1=CC=C([N+]([O-])=O)C(F)=C1
- CAS 데이터베이스
- 403-21-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xi,Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-37/38-36-22 | ||
| 안전지침서 | 26-36/37/39-37 | ||
| 위험 등급 | IRRITANT | ||
| HS 번호 | 29163990 |
3-Fluoro-4-nitrobenzoic acid C화학적 특성, 용도, 생산
용도
3-Fluoro-4-nitrobenzoic Acid is used in the synthesis of ABT-072, a non-nucleoside HCV NS5B polymerase inhibitor.Synthesis
To a solution of 3-fluoro-4-nitrobenzyl alcohol (2.97 g) in acetone (60 ml) was added Jones reagent (13 ml), prepared from chromic acid (26.7 g) and sulfuric acid (23 ml) in water (100 ml), dropwise at 0°C. The mixture was stirred on a ice-bath for 0.5 h and quenched with isopropanol (20 ml) to be concentrated in vacuo. The residue was dissolved in ethyl acetate (30 ml) and washed with water (30 ml X 3), and brine (30 ml X 1), successively. The organic layer was dried over sodium sulfate and concentrated in vacuo to obtain a yellow solid, that was triturated with hexane. 3-fluoro-4-nitrobenzoic acid as a pale yellow solid (2.94 g, 92%).
3-Fluoro-4-nitrobenzoic acid 준비 용품 및 원자재
원자재
Benzeneacetic acid, 3-fluoro-α-methyl-4-nitro-, methyl ester
3-Fluoro-4-nitrotoluene
3-Fluoro-4-nitrobenzyl alcohol 99%
5-METHYL-2-NITROANILINE
O-플루오로니트로벤젠
준비 용품
3-Fluoro-4-nitrobenzoic acid 공급 업체
글로벌( 296)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Baynoe Chem (Suzhou) Co., Ltd. | +86-512 65869404 +86-18934593683 |
sales06@baynoe.com | China | 292 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
| Hi-Tech Chemistry Corp | 0519-86626038 |
yuhh@hitechem.com | CHINA | 811 | 58 |
| Fluoropharm Co., Ltd. | +86-0571-85586753; +8613336034509 |
sales@fluoropharm.com | China | 1290 | 60 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Shanghai Arbor Chemical Co., Ltd. | 021-60451682 |
act@arborchemical.com | CHINA | 906 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 |
sales@dolonchem.com | CHINA | 2972 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2169 | 58 |
3-Fluoro-4-nitrobenzoic acid 관련 검색:
4-니트로안식향산 3-플루오로-4-니트로페놀 O-플루오로니트로벤젠 p-플루오로미트로벤젠 4-플루오로-3-니트로벤조산 플루오린(불소) 2,3,4,5-사불화플로로-6-니트로벤조산 4-플루오로-2-니트로벤조산 5-플루오로-2-니트로벤조산
3-Fluoro-4-nitroanisole
3-Fluoro-4-nitrobenzonitrile
3-Nitrobenzoic acid
4,5-Difluoro-2-nitrobenzoic acid
2,5-Difluoro-4-nitrobenzoic acid
METHYL 3-FLUORO-4-NITROBENZENECARBOXYLATE
2,6-DIFLUORO-3-NITROBENZOIC ACID
2-CHLORO-4-FLUORO-5-NITROBENZOIC ACID,2-Chloro-4-fluoro-5-nitrobenzoic acid 98%
3-FLUORO-2-NITROBENZOIC ACID