Anti-Sorting Nexin 4 C화학적 특성, 용도, 생산
용도
Monoclonal Anti-SNX4 antibody produced in mouse may be used in:
- immunoblotting
- immunocytochemistry
- enzyme-linked immunosorbent assay (ELISA)
일반 설명
This gene encodes a member of the sorting nexin family. Members of this family contain a phox (PX) domain, which is a phosphoinositide binding domain, and are involved in intracellular trafficking. This protein associated with the long isoform of the leptin receptor and with receptor tyrosine kinases for platelet-derived growth factor, insulin, and epidermal growth factor in cell cultures, but its function is unknown. This protein may form oligomeric complexes with family members. (provided by RefSeq)
Biochem/physiol Actions
Sorting Nexins 4 (SNX4) protein interacts with various tyrosine kinase receptors. SNX4 protein and amphiphysin 2 interact in the cell cytosol and on cytoplasmic vesicular structures. Overexpression of the SNX4 gene blocks the endocytosis of the transferrin receptor as efficiently as amphiphysin 2. The SNX4/amphiphysin 2 complex is essential for the control of the endosome fate after the formation of the endocytic vesicle.
Anti-Sorting Nexin 4 준비 용품 및 원자재
원자재
준비 용품
