Cefmetazole
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Cefmetazole 속성
- 녹는점
- 163-165?C
- 밀도
- 1.4380 (rough estimate)
- 굴절률
- 1.7400 (estimate)
- 저장 조건
- 2-8°C
- 용해도
- 메탄올(약간 가열)에 용해됨
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 2.65±0.50(Predicted)
- 색상
- 하얀색
- 수용성
- 물에 용해됨
- CAS 데이터베이스
- 56796-20-4(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 36/37/38-42/43 | ||
| 안전지침서 | 26-36 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | XI0372200 | ||
| HS 번호 | 2941906000 | ||
| 기존화학 물질 | KE-09094 |
Cefmetazole C화학적 특성, 용도, 생산
개요
Cefmetazole is a cephamycin with a nonaromatic side chain at C-7. In addition to a fairly characteristic second-generation cephalosporin antimicrobial spectrum, it possess fairly significant anti-antiaerobic activity. The ejection of its C-3 side chain leads to alcohol intolerance of the disulfuram type and prolonged clotting times.일반 설명
Cefmetazole was synthesized by Sankyo Co. in 1976starting with a biosynthetic cephamycin. It shows excellent activity against Serratia and Proteus, against which cefazolin is not active, and it has stronger activity than cefoxitin, another derivative of cephamycin. Cefmetazole is active against anaerobes and resistant to β-lactamase, but it is not active against Pseudomonas aeruginosa.화학적 성질
White Solid용도
Semi-synthetic antibiotic derived from Cephamycin. Antibacterial.정의
ChEBI: A cephalosporin antibiotic containg an N1-methyltetrazol-5-ylthiomethyl side-chain at C-3 of the parent cephem bicyclic structure.Antimicrobial activity
It is active against Pr. mirabilis, Pr. vulgaris, Morganella morganii, Yersinia spp.and most anaerobes. S. marcescens is moderately susceptible, but Ps. aeruginosa and E. faecalis are resistant. It is active against Mycobacterium fortuitum and some strains of M. chelonei. It is resistant to a wide range of β-lactamases.The serum concentration at the end of a 1 g intravenous infusion is around 77 mg/L. Plasma protein binding is 68%. It is principally excreted in the urine with a plasma half-life of c. 1.3 h; 70% is recovered over the first 6 h. In patients whose creatinine clearance is less than 10 mL/min, plasma levels are elevated and the plasma half-life is increased to around 15 h.
Side effects associated with the methylthiotetrazole group at position C-3 have been reported. Uses are similar to those of cefoxitin, but it is not widely available.
Cefmetazole 준비 용품 및 원자재
원자재
준비 용품
Cefmetazole 공급 업체
글로벌( 147)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12453 | 58 |
| Shaanxi TNJONE Pharmaceutical Co., Ltd | +86-13474506593 +86-13474506593 |
sarah@tnjone.com | China | 848 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8822 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |
| Neostar United (Changzhou) Industrial Co., Ltd. | +86-519-519-85557386 |
marketing1@neostarunited.com | China | 8349 | 58 |
| SIMAGCHEM CORP | +86-13806087780 |
sale@simagchem.com | China | 17367 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 |
marketing@targetmol.com | United States | 19892 | 58 |
Cefmetazole 관련 검색:
벤설프론 메틸 쿠레톡심메틸 메틸파라벤 아세트아미노펜 아크릴산메틸 아세틸 보조 효소 A 메틸 파라싸이온(메틸 파라티온) 브롬화 메틸
Ceftiofur sodium
Cefozopran
1-[[(6R,7R)-7-[[(2Z)-(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-2-carboxy-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-en-3-yl]methyl]-5,6,7,8-tetrahydro-quinolinium inner salt
Cefotetan
Methyl
CEFMETAZOLE ACID
Cefmetazole-Na,Sodium cefmetazole,Cefmetazole sodium
7-TMCA
3-AZETIDINOL
3-METHOXY-AZETIDINE