트리페닐포스페이트
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트리페닐포스페이트 속성
- 녹는점
- 48-50 °C (lit.)
- 끓는 점
- 244 °C/10 mmHg (lit.)
- 밀도
- 1.2055
- 증기 밀도
- 11.3 (vs air)
- 증기압
- 1.3 mm Hg ( 200 °C)
- 굴절률
- 1.563
- 인화점
- 435 °F
- 저장 조건
- Store below +30°C.
- 용해도
- H2O: 20°C에서 용해성0.0019g/L
- 물리적 상태
- 플레이크 크리스탈
- 색상
- 하얀색
- 냄새
- 냄새 없는
- 수용성
- 불용성
- Merck
- 14,9742
- BRN
- 1888236
- Henry's Law Constant
- 5.88 at 20 °C (approximate - calculated from water solubility and vapor pressure)
- 노출 한도
- TLV-TWA air 3 mg/m3 (ACGIH, OSHA, and NIOSH).
- 안정성
- 안정적인.
- InChIKey
- XZZNDPSIHUTMOC-UHFFFAOYSA-N
- LogP
- 4.6 at 20℃
- CAS 데이터베이스
- 115-86-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,N,F,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 22-38-40-48/20/22-50/53-52/53-36/37/38-67-66-36-11-51/53 | ||
안전지침서 | 36/37-61-60-24/25-22-36-26-16-24-9 | ||
유엔번호(UN No.) | UN 3077 9/PG 3 | ||
WGK 독일 | 2 | ||
RTECS 번호 | TC8400000 | ||
자연 발화 온도 | >500 °C | ||
TSCA | Yes | ||
위험 등급 | 9 | ||
포장분류 | III | ||
HS 번호 | 29190010 | ||
유해 물질 데이터 | 115-86-6(Hazardous Substances Data) | ||
독성 | LD50 orally in Rabbit: 3500 mg/kg LD50 dermal Rabbit > 7900 mg/kg | ||
IDLA | 1,000 mg/m3 | ||
기존화학 물질 | KE-34739 | ||
유해화학물질 필터링 | 2001-1-517 | ||
함량 및 규제정보 | 물질구분: 유독물질; 혼합물(제품)함량정보: 트리페닐인산 및 이를 25% 이상 함유한 혼합물 |
트리페닐포스페이트 C화학적 특성, 용도, 생산
화학적 성질
Triphenyl phosphate (TPP) is a colorless crystalline powder with a faint, phenol-like odor. Triphenyl phosphate is practically insoluble in water at 1.9 × 10 7 mg/l at 24 °C (Yalkowsky et al., 2010). It is very soluble in carbon tetrachloride (Haynes, 2010) and is soluble in most lacquers, solvents, thinners, and oils, as well as in alcohol, benzene, ether, chloroform, and acetone (Lewis, 1996). It begins to decompose at about 600 °C in inert gas, and in a large excess of air, complete combustion to carbon dioxide occurs in the range 800–900 °C (Lhomme et al., 1984). Hydrolysis of TPP occurs very slowly in acidic or neutral solutions, but occurs rapidly in alkaline solutions (Barnard et al., 1966).용도
Triphenyl phosphate is known as a product with manifold fields of applications regarding its qualities in particular as a flame retardant. One primary use is as a flame retardant in phenolic- and phenylene oxide-based resins for the manufacture of electrical and automobile components, for auto upholstery, and as a nonflammable plasticizer in cellulose acetate for photographic films. It has also been used to impregnate roofing paper. Triphenyl phosphate occurs as a plasticizer in various lacquers and varnishes (O'Neil, 2006), and as a component of lubricating oil and hydraulic fluids (ACGIH, 2012).정의
ChEBI: Triphenyl phosphate is an aryl phosphate resulting from the formal condensation of phosphoric acid with 3 mol eq. of phenol. It has a role as a flame retardant and a plasticiser. It is functionally related to a phenol.주요 응용
Triphenyl Phosphate is used in the insecticidal composition. It is also use in hydraulic liquids, and adhesives, inks, coatings, as a plasticizer in lacquers and varnishes, and as a substitute for camphor in celluloid materials to make the latter stable and fireproof.제조 방법
Triphenyl phosphate is prepared by reacting phosphorus pentoxide and phenol (Budavari, 2001), or by reacting phosphorus oxychloride and phenol (Snyder, 1990). On a larger scale phosphorus oxychloride and phenol are reacted in an esterification tank with heating. The HCL formed is trapped and condensed, while the crude triphenyl phosphate runs into a large tank where it is purified.반응 프로필
Organophosphates, such as Triphenyl phosphate, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.위험도
Toxic by inhalation. Cholinesterase inhibitor. Questionable carcinogen.?? ??
Non-industrial:An allergic reaction in a 67-year old woman to spectacle frames containing triphenyl phosphate was reported. Patch tests with analytical grade triphenyl phosphate in that individual indicated a reaction at concentrations as low as 0.05%. This observation was confirmed in another male patient (Carlsen et al 1986).
Industrial:
Occupational exposure of men engaged in manufacturing triphenyl phosphate produced a statistically significant reduction in erythrocyte acetylcholinesterase activity and plasma cholinesterase activity. There was no evidence of adverse clinical effects in men exposed to triphenyl phosphate for as long as 10 years. Exposure was to triphenyl phosphate mist, vapor, and dust at a weighted average air concentration of 3.5 mg/m3 (Sutton et al 1960).
화재위험
Noncombustible solid. Incompatibility— none.Safety Profile
Poison by subcutaneous route. Moderately toxic by ingestion. Absorbed slowly, particularly by skin contact. Not a potent cholinesterase inhibitor. Combustible when exposed to heat or flame. To fight fire, use CO2, dry chemical. When heated to decomposition it emits toxic fumes of POx. See also TRITOLYL PHOSPHATE.잠재적 노출
Triphenyl phosphate is used to impregnate roofing paper and as a fire-resistant plasticizer in plastics; for cellulose esters in lacquers and varnishes. Used in making adhesives, gasoline additives; flotation agents; insecticides, surfactants, antioxidants, and stabilizers. A substitute for camphor.환경귀착
Chemical/Physical. When an aqueous solution containing triphenyl phosphate (0.1 mg/L) and chlorine (3 to 1,000 mg/L) was stirred in the dark at 20 °C for 24 h, the benzene ring was substituted with one to three chlorine atoms (Ishikawa and Baba, 1988). The reported hydrolysis half-lives at pH values of 8.2 and 9.5 were 7.5 and 1.3 d, respectively (Howard and Doe, 1979).Decomposes at temperatures greater than 410 °C (Dobry and Keller, 1957)
신진 대사
Rat liver microsomal enzymes degraded triphenyl phosphate in the presence of NADPH, but also in the absence of NADPH. The product of incubation was diphenyl phosphate. It was clear that the reaction was cytochrome P-450-linked since the reaction was inhibited by carbon monoxide (Sasaki et al 1984). Goldfish liver microsomes metabolized only about 10% of triphenyl phosphate (Sasaki et al 1985). Houseflies treated with triphenyl phosphate were analyzed after 24 h and the presence of diphenyl p-hydroxyphenyl phosphate was confirmed (Eto et al 1975).운송 방법
UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.Purification Methods
Crystallise the phosphate from EtOH or pet ether (b 60-80o)/EtOH. [Cox & Westheimer J Am Chem Soc 80 5441 1958, Krishnakumar & Sharma Synthesis 558 1983, Cherbuliez in Organo Phosphorus Compounds (Kosolapoff & Maier eds) Wiley Vol 6 pp 211-577 1973, Beilstein 6 III 658, 6 IV 720.]Toxicity evaluation
Triphenyl phosphate(TPP) is neurotoxic, causing paralysis at high dosages. Like tri-o-cresyl phosphate (TOCP), it is a cholinesterase inhibitor. The acute oral toxicity is low. The acute toxicity via subcutaneous administration is low to moderate. The toxic symptoms from high dosages in test animals were tremor, diarrhea, muscle weakness, and paralysis.LD50 value, oral (mice): 1320 mg/kg
LD50 value, subcutaneous (cats): 100 mg/kg
Cleveland et al. (1986) investigated the acute and chronic toxicity to various species of freshwater fish of phosphate ester compounds containing TPP. The adverse toxic effects occurred at exposure concentrations of 0.38–1.0 mg/L.
비 호환성
Incompatible with strong oxidizers; strong acids; nitrates may cause fire or explosions. Phosphates are incompatible with antimony pentachloride, magnesium, silver nitrate, zinc acetate.폐기물 처리
Incinerate in furnace equipped with alkaline scrubber.트리페닐포스페이트 준비 용품 및 원자재
원자재
1-옥타놀
페놀
염소(기체)
트리페닐 포스파이트
알파-메틸 스타이렌
삼염화 인
Phenyl dichlorophosphate
디펜닐포소릴클로라이드
Phosphorous acid, dimethyl phenyl ester
DIPHENYL METHYLPHOSPHONATE
O,O,O-트라이페닐포스포로싸이오산
DIPHENYL PHOSPHORAMIDATE
트리메틸포스파이트
요오드 메탄
준비 용품
트리페닐포스페이트 공급 업체
글로벌( 606)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
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Hebei Duling International Trade Co. LTD | +8618032673083 |
sales05@hbduling.cn | China | 15745 | 58 |
Tianjin Zhongxin Chemtech Co., Ltd. | +86-022-66880623 +8618622897568 |
sales@tjzxchem.com | China | 559 | 58 |
Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
Changzhou waston chemical technology Co.,Ltd | +86-051985861892 +8618112881323 |
info@wastonchem.com | China | 237 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7786 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Dalian Richfortune Chemicals Co., Ltd | 0411-84820922 8613904096939 |
sales@richfortunechem.com | China | 303 | 57 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 |
jack.li@time-chemicals.com | China | 1807 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |