ChemicalBook >제품 카탈로그 >6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 구조식 이미지

카스 번호:: 1231930-33-8

상품명:: 6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole

동의어(영문):: 6-Bromo-4-fluoro-2-methyl-1-(1-methylethyl)-1H-benzimidazole;Abemaciclib Impurity 1;Abemaciclib Impurity 1 D5;Abemaciclib Impurity 1 D12;6-bromo-4-fluoro-2-methyl-1-(1-methylethyl)-;6-Bromo-4-fluoro-1-isopropyl-2-methylbenzimidazole;6-bromo-4-fluoro-2-methyl-1-propan-2-ylbenzimidazole;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzimidazole;6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole;6-bromo-4-fluoro-2-methyl-1-(propan-2-yl)-1H-1,3-benzodiazole

CBNumber:: CB92500134

분자식:: C11H12BrFN2

포뮬러 무게:: 271.13

MOL 파일:: 1231930-33-8.mol

속성

안전

용도

공급 업체 200

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 속성

끓는 점: 353.4±22.0 °C(Predicted)

밀도: 1.49

저장 조건: Sealed in dry,Room Temperature

산도 계수 (pKa): 3.48±0.10(Predicted)

InChI: InChI=1S/C11H12BrFN2/c1-6(2)15-7(3)14-11-9(13)4-8(12)5-10(11)15/h4-6H,1-3H3

InChIKey: SJQZRZLUEGCXFN-UHFFFAOYSA-N

SMILES: C1(C)N(C(C)C)C2=CC(Br)=CC(F)=C2N=1

안전

HS 번호	2933998090

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole C화학적 특성, 용도, 생산

용도

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole is a pharmaceutical intermediate. It can be used in the preparation of Abemaciclib, a kinase inhibitor for the treatment of adult patients with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer who have experienced disease progression following endocrine therapy and prior chemotherapy.

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 준비 용품 및 원자재

원자재

1H-Benzimidazole, 5-bromo-7-fluoro-2-methyl- Ethanimidamide,N-(1-methylethyl)- EthaniMidaMide, N-(4-broMo-2,6-difluorophenyl)-N'-(1-Methylethyl)- 4-Bromo-2,6-difluoroaniline N-Isopropylacetamide 아세톤

준비 용품

1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 공급 업체

글로벌( 200)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Lianhe Aigen Pharmatech Co.,Ltd.	+86-18918657159 +86-18918657159	sales-Aigen@lianhetech.com	China	305	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7786	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Shanghai Yingrui Biopharma Co.,Ltd	21-33585366	export01@shyrchem.com	CHINA	1320	58
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58

6-Bromo-4-fluoro-1-isopropyl-2-methyl-1H-benzo[d]imidazole 관련 검색:

6-BroMo-4-fluoro-3-Methylindazole PERFLUOROPOLYALKYL ETHER GALDEN (TM) HT70 Hexafluoroisopropyl methyl ether 1H-BenziMidazole, 4-fluoro-2-Methyl-1-(1-Methylethyl)-6-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)- 2-bromo-8-fluoro-4,5-dihydro-1H-azepino[5,4,3-cd]indol-6(3H)-one PF-01367338 5-((4-Ethylpiperazin-1-yl)methyl)pyridin-2-amine 4-(8-fluoro-6-oxo-3,4,5,6-tetrahydro-1H-azepino[5,4,3-cd]indol-2-yl)benzaldehyde 1H-BenziMidazole, 6-(2-chloro-5-fluoro-4-pyriMidinyl)-4-fluoro-2-Methyl-1-(1-Methylethyl)-