알라닐글루타민

알라닐글루타민
알라닐글루타민 구조식 이미지
카스 번호:
39537-23-0
한글명:
알라닐글루타민
동의어(한글):
알라닐글루타민
상품명:
L-Alanyl-L-Glutamine
동의어(영문):
ALA-GLN;Alu-Gln;ALANYL-GLUTAMINE;N(2)-L-ALANYL-L-GLUTAMINE;DIPEPTIVEN;Ala-Gln-OH;H-ALA-GLN-OH;L-ALANY-L-GLUTAMINE;L-Alanyl-L-Glutamine Alanyl Glutamine;Aln-Gln
CBNumber:
CB9253481
분자식:
C8H15N3O4
포뮬러 무게:
217.22
MOL 파일:
39537-23-0.mol
MSDS 파일:
SDS

알라닐글루타민 속성

녹는점
215 °C
끓는 점
615℃
밀도
1.305±0.06 g/cm3(Predicted)
증기압
0-1000Pa at 20-313.7℃
FEMA
4712 | L-ALANYL-L-GLUTAMINE
RTECS 번호
MA2275262
굴절률
10 ° (C=5, H2O)
인화점
>110°(230°F)
저장 조건
2-8°C
용해도
물 (난용성)
물리적 상태
액체
산도 계수 (pKa)
3.12±0.10(Predicted)
색상
하얀색
수소이온지수(pH)
pH(50g/l, 25℃) : 5.0~6.0
냄새
순한맛
수용성
물에 용해됩니다.
JECFA Number
2121
안정성
흡습성
InChIKey
HJCMDXDYPOUFDY-AKGZTFGVSA-N
LogP
-4.6 at 22℃ and pH6.3
표면장력
70mN/m at 1g/L and 20℃
CAS 데이터베이스
39537-23-0(CAS DataBase Reference)

안전

위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 23-24/25-36-26
WGK 독일 1
HS 번호 29241990

알라닐글루타민 C화학적 특성, 용도, 생산

개요

L-Alanyl-L-glutamine is a synthetic glutamine dipeptide that can attenuate oxidative stress in rodent models when administered at doses of 0.75-1.5 mg/kg. In vivo, the parenteral administration of L-alanyl-L-glutamine to Swiss mice yields higher plasma glutamine levels compared to enteral administration. In vitro, the addition of this dipeptide (50 mM) to cultures of antibody-producing CHO cells reduces apoptosis and promotes antibody production. Treatment of insulin-secreting BRIN-BD11 β-cells with L-alanyl-L-glutamine (2 mM) protects against the inflammatory effects of exposure to lipopolysaccharide-treated primary macrophages.

화학적 성질

White Solid

용도

A substitute for glutamine in mammalian cell culture media; stable to heat-sterilization.L-Alanyl-L-glutamine is used as a component in pharmaceuticals, cosmetics and food products. It is a stable Gln dipeptide, which protects mice against the jejunal crypt depletion in the setting of dietary protein and fat deficiency. It provides nutritional requirements, improves intestinal health and enhances the immune system. It is also involved in various clinical studies such as cancer treatment, radiation and chemotherapy. It finds application in biotechnology as a component for mammalian cell culture medium. It improves pancreatic beta-cell function, maintaining the mitochondrial metabolism and stimulus-secretion coupling essential for insulin release.

정의

ChEBI: A dipeptide formed from L-alanyl and L-glutamine residues.

알라닐글루타민 준비 용품 및 원자재

원자재

준비 용품


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