Tenofovir Alafenamide
|
|
Tenofovir Alafenamide 속성
- 녹는점
- >119°C (dec.)
- 끓는 점
- 640.4±65.0 °C(Predicted)
- 밀도
- 1.39±0.1 g/cm3(Predicted)
- 저장 조건
- 2-8°C(protect from light)
- 용해도
- 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 산도 계수 (pKa)
- 4.21±0.10(Predicted)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 색상
- 흰색에서 황백색까지
- 안정성
- 흡습성
- InChIKey
- LDEKQSIMHVQZJK-QTJFZWIYNA-N
- SMILES
- C(OC(C)C)(=O)[C@H](C)NP(CO[C@H](C)CN1C2=C(N=C1)C(N)=NC=N2)(OC1=CC=CC=C1)=O |&1:6,12,r|
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
Tenofovir Alafenamide C화학적 특성, 용도, 생산
개요
Tenofovir alafenamide fumarate is an oral phosphonoamidate prodrug of the reverse transcriptase inhibitor tenofovir. It was approved by the USFDA for the treatment of chronic hepatitis B virus infection with compensated liver disease. Tenofovir alafenamide fumarate was discovered and developed by Gilead as a potentially safer form of the previously approved tenofovir disoproxil fumarate (Viread).용도
Tenofovir Alafenamide, also known as Tenofovir Impurity 51, is a prodrug of Tenofovir (T018500), which is a reverse transcriptase inhibitor used to treat HIV and Hepatitis B.정의
ChEBI: An L-alanine derivative that is isopropyl L-alaninate in which one of the amino hydrogens is replaced by an (S)-({[(2R)-1-(6-amino-9H-purin-9-yl)propan-2-yl]oxy}methyl)( henoxy)phosphoryl group. A prodrug for tenofovir, it is used (as the fumarate salt) in combination therapy for the treatment of HIV-1 infection.Tenofovir Alafenamide 준비 용품 및 원자재
원자재
L-Alanine Isopropyl Ester Hydrochloride
Tenofovir Related Compound 6
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
준비 용품
Tenofovir Alafenamide 공급 업체
글로벌( 355)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Guangzhou Tosun Pharmaceutical Limited | +8618922120635 |
sales@toref-standards.com | China | 1000 | 58 |
Alpha Biopharmaceuticals Co., Ltd | +86-411-39042497 +8613921981412 |
sales@alphabiopharm.com | China | 886 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Nanjing Gold Pharmaceutical Technology Co. Ltd. | 025-84209270 15906146951 |
CHINA | 115 | 55 | |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 |
fandachem@gmail.com | China | 9348 | 55 |
Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 |
product@chemlin.com.cn | CHINA | 3012 | 60 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 |
sales@fine-chemtech.com | CHINA | 885 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
Tenofovir Alafenamide 관련 검색:
염화 티오닐
D-Alanine Isopropyl Ester HCl
6N-HydroxyMethyl Tenofovir Disoproxil
Tenofovir Related Compound 14
Tenofovir Alafenamide PMPA Impurity
Pimecrolimus
9-[(R)-2-(Phosphonomethoxy)propyl]adenine monohydrate
Tenofovir disoproxil
9-Propenyladenine
Tenofovir
Tenofovir Alafenamide Impurity 30
DNA, SINGLE STRANDED, IMM. ON CELLULOSE, FROM CALF THYMUS*
diisopropyl 2,2'-((((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphoryl)bis(azanediyl))(2S,2'S)-dipropionate compound with methane (1:1)
Tenofovir Related Compound 6
Tenofovir disoproxil fumarate
phenyl hydrogen ((((R)-1-(6-amino-9H-purin-9-yl)propan-2-yl)oxy)methyl)phosphonate
Tenofovir alafenamide hemifumarate
GS-7340 (fuMarate)