다이하이드로콜레스테롤
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다이하이드로콜레스테롤 속성
- 녹는점
- 138-142 °C
- 알파
- D22 +24.2° (c = 1.3 in chloroform)
- 끓는 점
- 454.32°C (rough estimate)
- 밀도
- 0.9506 (rough estimate)
- 굴절률
- 1.5250 (estimate)
- 저장 조건
- -20°C
- 용해도
- 클로로포름: 0.1 g/mL, 투명, 무색
- 물리적 상태
- 고체
- 산도 계수 (pKa)
- 15.14±0.70(Predicted)
- 수용성
- 물에 불용성.
- Merck
- 14,2200
- BRN
- 2418594
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- LogP
- 10.065 (est)
- CAS 데이터베이스
- 80-97-7(CAS DataBase Reference)
- NIST
- Cholestanol(80-97-7)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 22-38-40-48/20/22-67-36/38-20-63 | ||
| 안전지침서 | 24/25-36/37-22-26 | ||
| 유엔번호(UN No.) | UN 1888 6.1/PG 3 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | FZ6350000 | ||
| TSCA | Yes | ||
| HS 번호 | 2906 13 10 |
다이하이드로콜레스테롤 C화학적 특성, 용도, 생산
개요
Cholestanol is a cholesterol metabolite formed by oxidation and an intermediate in the biosynthesis of chenodeoxycholic acid . Cholestanol (10 μg/ml) induces apoptosis in cornea and lens epithelial cells and increases the activity of IL-1β converting enzyme (ICE) and CPP32 proteases. Dietary administration of 1% cholestanol to mice increases serum and liver cholestanol levels and leads to corneal opacities and gallstones and in rats it leads to cholestanol deposition in the cerebellum. Cholestanol levels are increased in plasma of patients with cerebrotendinous xanthomatosis (CTX), a disease characterized by a deficiency in the mitochondrial enzyme sterol 27-hydrolylase (CYP27A1) that leads to progressive neurological symptoms.화학적 성질
white powder용도
5α-Cholestan-3β-ol is a carbon stanol formed from biohydrogenation of Cholesterol (C432501) in the gut. Studies have also examined the conversion of 5α-Cholestan-3β-ol catalyzed by 3-β-hydroxysteroid dehydrogenase of rat liver.정의
ChEBI: A cholestanoid that is (5alpha)-cholestane substituted by a beta-hydroxy group at position 3.일반 설명
Cholestanol is a 5α-dihydro derivative of cholesterol. It acts as a marker for cholesterol absorption. Cholestanol is a steroid with 27 carbon atoms.Purification Methods
Purify 5--cholestan-3-ol via acetylation, crystallisation and de-acetylation, then recrystallisation from EtOH or slightly aqueous EtOH, or MeOH. Its solubility is: 0.5% (MeOH) and 1% (EtOH) at 25o. [Mizutani & Whitten J Am Chem Soc 107 3621 1985.] The acetate has m 114-115o from EtOAc/MeOH and, [] D 20 +13o (c 2, CHCl3). [Bruce & Ralls Org Synth Col Vol II 191 1943, Beilstein 6 IV 3577.]다이하이드로콜레스테롤 준비 용품 및 원자재
원자재
CHOLESTANOL ACETATE
3β-(Tosyloxy)-5α-cholestane
5ALPHA-CHOLESTAN-3-ONE
DESMOSTEROL
4-Cholesten-3-one
준비 용품
다이하이드로콜레스테롤 공급 업체
글로벌( 192)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 |
figo.gao@foxmail.com | China | 6992 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shanghai Daeyeon Chemicals Co., Ltd | 021-64478606 +8615900664856 |
daeyeon001@vip.163.com | China | 2062 | 58 |
| changzhou huayang technology co., ltd | +8615250961469 |
2571773637@qq.com | China | 9821 | 58 |
| Alfa Chemistry | +1-5166625404 |
Info@alfa-chemistry.com | United States | 21317 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 |
sales@invivochem.cn | United States | 6393 | 58 |
| Shaanxi Didu New Materials Co. Ltd | +86-89586680 +86-13289823923 |
1026@dideu.com | China | 9448 | 58 |
다이하이드로콜레스테롤 관련 검색:
콜레스테롤 인산 나트륨, 이염기 제1인산암모늄 수소화 칼륨 프탈산 모노알루미늄 인산염 용액 디기토닌
Diethyl 1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylate
5α-Cholestane
Dipotassium hydrogen phosphate trihydrate
DIHYDROLIPOIC ACID
Hecogenin
HECOGENIN ACETATE
TOMATINE
Tigogenin
TOMATIDINE
DIHYDROCHOLETH-30
Dihydrocholesteryl oleate
Tomatidine hydrochloride