BMS-791325

BMS-791325 구조식 이미지
카스 번호:
958002-36-3
상품명:
BMS-791325
동의어(영문):
BMS-791325;BMS 791325-08;BMS-791325 1G;Beclabuvir HCl;BMS-791325 HCl;PubChem ID: 72722244;BMS 791325 hydrochloride;Beclabuvir hydrochloride;BMS-791325 Beclabuvir hydrochloride
CBNumber:
CB92716748
분자식:
C36H46ClN5O5S
포뮬러 무게:
696.3
MOL 파일:
958002-36-3.mol

BMS-791325 속성

안전

BMS-791325 C화학적 특성, 용도, 생산

효소 저해제

This potent allosteric inhibitor (FW = 673.87 g/mol) targets hepatitis C virus NS5B polymerase IC50 <0.5 nM (biochemical assay) and EC50 = 0.8-6 nM (replicon assay). Unlike prior cyclopropyl-fused indolobenzazepine inhibitors, BMS-791325 has improved solubility and membrane permeability properties as well as reduced off-target activities, directed most notably against human pregnane X receptor (hPXR) transactivation.

BMS-791325 준비 용품 및 원자재

원자재

준비 용품


BMS-791325 공급 업체

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