Pravastatin sodium
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Pravastatin sodium 속성
- 녹는점
- 171.2-173 °C
- 저장 조건
- 2-8°C
- 용해도
- H2O: 19 mg/mL
- 물리적 상태
- 가루
- 색상
- 하얀색
- Merck
- 14,7714
- BCS Class
- 1 (CLogP), 3 (LogP)
- 안정성
- 흡습성
- CAS 데이터베이스
- 81131-70-6(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | F,C | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 11-34 | ||
| 안전지침서 | 16-26-36/37/39-45 | ||
| 유엔번호(UN No.) | 3077 | ||
| WGK 독일 | 2 | ||
| RTECS 번호 | QJ7185000 | ||
| 위험 등급 | 9 | ||
| 포장분류 | III | ||
| HS 번호 | 29329990 |
| 그림문자(GHS): |
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| 신호 어: | Warning | ||||||||||||||||||||||||||||||||
| 유해·위험 문구: |
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| 예방조치문구: |
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Pravastatin sodium C화학적 특성, 용도, 생산
화학적 성질
White Crystalline Powder용도
Pravastatin sodium is the salt of pravastatin, a ring-opened member of the statin family. Pravastatin is produced biosynthetically from compactin (mevastatin) by a number of microorganisms, notably Absidia, Cunninghamella, Syncephalastrum, Nocardia or Streptomyces. Typically, statins like compactin, lovastatin and simvastatin possess a β-hydroxy lactone ring which is a pro-drug for the readily ring-opened dihydroxyacid generally regarded as the active HMG-CoAreductase inhibitor. Importantly, the free carboxylic acid enables pravastatin to be freely water soluble within biological pH ranges.정의
ChEBI: An organic sodium salt that is the sodium salt of pravastatin. A reversible inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA), it is used for lowering cholesterol and preventing cardiovascular disease. It is one of the lower potency statins, but has the advantage of fewer side effects compared with lovastatin and simvastatin.일반 설명
A water-soluble, competitive 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitor that potently blocks in vivo cholesterol synthesis (Ki = ~1 nM). Offers cardioprotection. Also acts as an immunomodulator and an inhibitor of ras p21 isoprenylation.생물학적 활성
Water-soluble, competitive inhibitor of 3-hydroxy-3-methyl coenzyme A (HMG-CoA) reductase. Potently blocks cholesterol synthesis in vivo (K i ~ 1 nM) and displays cardioprotective properties.Pravastatin sodium 준비 용품 및 원자재
원자재
준비 용품
Pravastatin sodium 공급 업체
글로벌( 370)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 |
sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21695 | 55 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 |
sales@amoychem.com | China | 6387 | 58 |
| HubeiwidelychemicaltechnologyCo.,Ltd | 18627774460 |
faith@widelychemical.com | CHINA | 742 | 58 |
| BOC Sciences | +1-631-485-4226 |
inquiry@bocsci.com | United States | 19553 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Shenzhen Excellent Biotech Co., Ltd. | 13480692018 |
ramyan@ex-biotech.com | CHINA | 954 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; |
factory@coreychem.com | China | 29826 | 58 |