AZURIN

AZURIN 구조식 이미지
카스 번호:
12284-43-4
상품명:
AZURIN
동의어(영문):
AZURIN;AZURIN FROM PSEUDOMONAS AERUGINOSA;Azurin (Pseudomonas fluorescens protein);Azurin from Pseudomonas aeruginosa, lyophilized powder
CBNumber:
CB9325753
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file
MSDS 파일:
SDS

AZURIN 속성

저장 조건
-20°C
물리적 상태
동결건조된 분말

안전

안전지침서 22-24/25
WGK 독일 3
F 고인화성물질 8

AZURIN C화학적 특성, 용도, 생산

용도

Azurin has been used:
  • in the cytotoxicity and cell viability studies in human osteosarcoma cell line
  • for the functionalization of silicon nitride cantilevers for interaction studies
  • for coating gold surface and insulating functionalized oxide surfaces of silicon oxide and mica

Biochem/physiol Actions

Azurin is a metalloprotein in the family of cupredoxins. It preferentially enters cancer cells over normal cells and induces apoptosis. Azurin has structural similarities to ephrinB2, and in fact binds the ephrin receptor tyrosine kinase EphB2 to initiate cell signaling that is involved in cancer progression. Azurin inhibits autophosphorlyation of the EphB2 tyrosine residue, interfering with upstream cell signaling and contributing to cancer cell growth inhibition.

Purification Methods

Azurin with A625/280 = 0.56 is purified by gel chromatography on G-25 Sephadex with 5mM phosphate pH 7 buffer as eluent [Cho et al. J Phys Chem 91 3690 1987]. It is a blue Cu protein used in biological electron transport, and its reduced form is obtained by adding a slight excess of Na2S2O4. [See Structure and Bonding Springer Verlag, Berlin 23 1 1975.]

AZURIN 준비 용품 및 원자재

원자재

준비 용품


AZURIN 공급 업체

글로벌( 7)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512
info@tianfuchem.com China 21695 55
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51471 80
Energy Chemical 021-58432009 400-005-6266
marketing1@energy-chemical.com China 44894 58

Copyright 2019 © ChemicalBook. All rights reserved