alpha-Lobeline hydrochloride

alpha-Lobeline hydrochloride 구조식 이미지
카스 번호:
134-63-4
상품명:
alpha-Lobeline hydrochloride
동의어(영문):
Lobelin Hydrochlorde;LOBELINE HYDROCHLORIDE;(-)-id;a-Lobeline;A-LOBELINE HCL;LOBELINE HCL, A-;(-)-LOBELINE HCL;Einecs 205-150-2;ALPHA-LOBELIN HCL;Lobeline HCl salt
CBNumber:
CB9404885
분자식:
C22H28ClNO2
포뮬러 무게:
373.92
MOL 파일:
134-63-4.mol

alpha-Lobeline hydrochloride 속성

녹는점
183-185 °C (dec.)(lit.)
알파
D20 -43° (c = 2)
굴절률
-57.5 ° (C=1, H2O)
저장 조건
Inert atmosphere,Room Temperature
용해도
H2O: 25 mg/mL
물리적 상태
가루
색상
흰색에서 황백색까지
optical activity
[α]20/D 56.8°, c = 2 in H2O
Merck
14,5551
BRN
3920196
LogP
3.610 (est)
CAS 데이터베이스
134-63-4(CAS DataBase Reference)
안전
  • 위험 및 안전 성명
위험품 표기 T
위험 카페고리 넘버 23/25
안전지침서 36/37/39-45
유엔번호(UN No.) UN 1544 6.1/PG 3
WGK 독일 3
RTECS 번호 OJ8490100
F 고인화성물질 8
위험 등급 6.1(b)
포장분류 III
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
4 0

alpha-Lobeline hydrochloride C화학적 특성, 용도, 생산

개요

(–)-Lobeline is an alkaloid that has been found in Lobelia and has diverse biological activities. It binds to nicotinic acetylcholine receptors (nAChRs) in rat brain homogenates (Ki = 4 nM) and has antinociceptive effects in the tail-flick assay in mice. (–)-Lobeline (0.3 and 0.9 mg/kg) reduces the number of errors in a repeated acquisition procedure in the radial arm maze in rats. It also decreases immobility time in the forced swim test and feeding latency in the novelty suppressed feeding test, indicating antidepressant-like activity, in mice when administered at doses of 1 and 4 mg/kg.

화학적 성질

White to Off-White Solid

용도

A neuronal nicotinic acetylcholine receptor agonist. A respiratory stimulant

생물학적 활성

High affinity nicotinic receptor ligand, with a K i value of 4.4 nM in rat brain.

alpha-Lobeline hydrochloride 준비 용품 및 원자재

원자재

준비 용품


alpha-Lobeline hydrochloride 공급 업체

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career henan chemical co
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marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671
sales@tnjchem.com China 34572 58

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