발렌센

발렌센
발렌센 구조식 이미지
카스 번호:
4630-07-3
한글명:
발렌센
동의어(한글):
발렌센
상품명:
VALENCENE
동의어(영문):
Valencen;(1R,7R,8aS)-1,2,3,5,6,7,8,8a-Octahydro-1,8a-dimethyl-7-(1-methylethenyl)naphthalene;FEMA 3443;(3R,4aS,5R)-4a,5-Dimethyl-3-(prop-1-en-2-yl)-1,2,3,4,4a,5,6,7-octahydronaphthalene;Naphthalene, 1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-, (1R,7R,8aS)-;VALENCENE;NSC 148969;Valencene T;VALENCENE 85;VALENCENE775
CBNumber:
CB9420232
분자식:
C15H24
포뮬러 무게:
204.35
MOL 파일:
4630-07-3.mol
MSDS 파일:
SDS

발렌센 속성

끓는 점
274 °C(lit.)
밀도
0.92 g/mL at 25 °C(lit.)
FEMA
3443 | VALENCENE
굴절률
n20/D 1.504(lit.)
인화점
>230 °F
저장 조건
2-8°C
용해도
클로로포름(약간 용해됨), 에틸아세테이트(약간 용해됨), 메탄올(약간 용해됨)
용해도
클로로포름(약간), 에틸아세테이트(약간), 메탄올(약간)에 용해됨
물리적 상태
기름
색상
무색
Specific Gravity
0.92
냄새
디프로필렌 글리콜 중 10.00%. 달콤한 신선한 감귤류 자몽 우디 오렌지 아스프린 건조 녹색 기름진
?? ??
감귤류
optical activity
[α]22/D +90°, neat
Hydrolytic Sensitivity
1: no significant reaction with aqueous systems
JECFA Number
1337
BRN
3539153
안정성
감광성
LogP
6.29
EPA
Naphthalene, 1,2,3,5,6,7,8,8a-octahydro-1,8a-dimethyl-7-(1-methylethenyl)-, (1R,7R,8aS)- (4630-07-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
안전지침서 23-24/25
WGK 독일 3
그림문자(GHS): GHS hazard pictograms
신호 어: Danger
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H304 삼켜서 기도로 유입되면 치명적일 수 있음 흡인 유해성물질 구분 1 위험 GHS hazard pictograms
예방조치문구:
P301+P310 삼켰다면 즉시 의료기관(의사)의 진찰을 받으시오.
P331 토하게 하지 마시오.
P405 밀봉하여 저장하시오.
P501 ...에 내용물 / 용기를 폐기 하시오.
NFPA 704
1
0 0

발렌센 C화학적 특성, 용도, 생산

개요

(+)-Valencene is a sesquiterpene that has been found in C. sativa and is an aromatic component of orange essence oil. (+)-Valencene (50 μM) induces heme oxgenase-1 (HO-1) expression in macrophages and inhibits the expression of inducible nitric oxide synthase (iNOS), the production of nitric oxide (NO), and the release of high-mobility group box-1 (HMGB1) in RAW 264.7 cells stimulated with LPS. It also increases the survival rate in a mouse model of sepsis induced by cecal ligation and puncture. (+)-Valencene has been used in the synthesis of nootkatone .

화학적 성질

clear colorless to yellowish liquid

출처

Reported found in citrus fruits, orange peel, orange juice, bitter orange peel oil, lemon peel oil, grapefruit juice, grapefruit peel oil, kumquat peel oil, leaves and stalk of celery, clove stem, Thymus vulgaris L., fresh mango, globe artichoke, cardamom, mangosteen and cocoa.

용도

Valencene is a sesquiterpene and an essential oil component found in a variety of plants, and has been shown to have functional antioxidant, antiradical and antimicrobial properties.

정의

ChEBI: A carbobicyclic compound and sesquiterpene that is 1,2,3,4,4a,5,6,7-octahydronaphthalene which is substituted a prop-1-en-2-yl group at position 3 and by methyl groups at positions 4a and 5 (the 3R,4aS,5R diastereoisomer).

제조 방법

By a Wolf–Kishner reduction of nootkatone.

일반 설명

Valencene is the major sesquiterpene aroma constituent of orange peel oil. It is mainly used as a starting material to synthesize nootkatone, an important flavor compound of grapefruit.

발렌센 준비 용품 및 원자재

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