2-Bromophenylboronic acid
|
|
2-Bromophenylboronic acid 속성
- 녹는점
- 113 °C(lit.)
- 끓는 점
- 329.2±44.0 °C(Predicted)
- 밀도
- 1.67±0.1 g/cm3(Predicted)
- 저장 조건
- Keep in dark place,Sealed in dry,Room Temperature
- 용해도
- 아세토니트릴(약간 용해됨), 클로로포름(약간 용해됨), DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 가루
- 산도 계수 (pKa)
- 8.25±0.58(Predicted)
- 색상
- 흰색에서 황백색까지
- 수용성
- 메탄올에 용해됩니다. 물에 약간 용해됩니다.
- BRN
- 8542615
- CAS 데이터베이스
- 244205-40-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
위험품 표기 | Xn,Xi | ||
---|---|---|---|
위험 카페고리 넘버 | 36/37/38-22 | ||
안전지침서 | 37/39-26 | ||
WGK 독일 | 3 | ||
위험 등급 | IRRITANT | ||
HS 번호 | 29319090 |
2-Bromophenylboronic acid C화학적 특성, 용도, 생산
화학적 성질
White to off-white powder용도
2-Bromobenzeneboronic acid is a boronic acid derivative that is widely used in organic synthesis for carbon-carbon bond formation. In Suzuki coupling, aryl halides and boronic acid aryl or vinyl esters or boronic acids are coupled using Pd(PPh3)4.주요 응용
2-Bromophenylboronic Acid is used as an inhibitor of the hormone sensitive lipase.Catalyzes the formation of amide bonds from amines and carboxylic acids.
Used to promote greener amidations of carboxylic acids and amines in catalytic amounts. This technology avoids the requirement of preactivation of the carboxylic acid or use of coupling reagents.
It is also an important intermediate for Organic Light-Emitting Diod ( OLED) .
제조 방법
2-Bromophenylboronic acid synthesis: take 2-bromoaniline as raw material, synthesize the intermediate 1-Bromo-2-iodobenzene through diazotization and iodination, and then carry out magnesium iodide exchange with isopropylmagnesium bromide to synthesize o-bromophenylmagnesium bromide, It is then subjected to substitution reaction with trimethyl borate to synthesize methyl o-bromophenylboronic acid, and then hydrolyzed to synthesize 2-bromophenylboronic acid.2-Bromophenylboronic acid 준비 용품 및 원자재
원자재
준비 용품
4-fluoro-N-(1-hydroxy-3,3-dimethyl-1,3-dihydrobenzo[c][1,2]oxaborol-6-yl)-2-(trifluoromethyl)benzamide(WXG02326)
4-BROMOPHENYL TRIFLUOROMETHANESULFONATE
5,11-dihydro-5-phenylindolo[3,2-b]carbazole
3,3-diMethylbenzo[c][1,2]oxaborol-1(3H)-ol
2'-BROMOBIPHENYL-2-YLCARBOXALDEHYDE
2-BROMO-3'-METHYLBENZOPHENONE
2-Bromophenylboronic acid 공급 업체
글로벌( 379)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 |
18522618860@163.com | China | 694 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7786 | 58 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 |
info@dakenam.com | China | 15928 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32480 | 60 |
Beijing Green Guardee Technology Co., Ltd | 86-010-69706062 |
sales2@greenguardee.com | CHINA | 650 | 58 |
career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
Shanghai Arbor Chemical Co., Ltd. | 021-60451682 |
act@arborchemical.com | CHINA | 906 | 58 |
Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 |
sales@finerchem.com | China | 2967 | 58 |
Accela ChemBio Inc. | (+1)-858-699-3322 |
info@accelachem.com | United States | 19965 | 58 |
2-Bromophenylboronic acid 관련 검색:
디브로모벤젠(1,3-) 페닐붕산 시트르산 2-브로모페닐아세트산 3-브로모아니졸 붕산 아연 트리페닐포스핀 디브로모벤젠(1,2-) 2-페닐페놀 2-브로모플로로벤젠
2-Bromobenzonitrile
Ascoric Acid
2-BROMO-3-ETHOXY-6-FLUOROPHENYLBORONIC&
3-BROMO-6-FLUORO-3-PROPOXYPHENYLBORONIC&
2-BROMO-5-METHOXYPHENYLBORONIC ACID
2-Bromo-6-fluoro-3-methoxyphenylboronic acid
(2,6-DIBROMO-5-METHOXY)BENZENEBORONIC ACID
Phenylacetone