XANTHOTOXOL
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XANTHOTOXOL 속성
- 녹는점
- 250°C
- 끓는 점
- 428.1±45.0 °C(Predicted)
- 밀도
- 1.526±0.06 g/cm3(Predicted)
- 저장 조건
- 2-8°C
- 용해도
- DMSO(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 고체
- 물리적 상태
- 단단한 모양
- 산도 계수 (pKa)
- 5.74±0.20(Predicted)
- 색상
- 라이트 베이지부터 다크 브라운까지
- LogP
- 1.405 (est)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험 카페고리 넘버 | 25 | ||
|---|---|---|---|
| 안전지침서 | 20-45-24/25 | ||
| 유엔번호(UN No.) | 2810 | ||
| HS 번호 | 29329990 |
XANTHOTOXOL C화학적 특성, 용도, 생산
개요
Xanthotoxol is a coumarin and a major component in C. monnieri that has diverse biological activities. It inhibits proliferation of HeLa and HepG2 cells in vitro (IC50s = 23.59 and 15.57 μM, respectively). Xanthotoxol increases histamine release from mast cells and decreases secretion of TNF-α, IL-4, and IL-1β from RBL-2H3 cells induced by DNP-human serum albumin (DNP-HSA). It is nematocidal against M. incognita (IC50 = 68 mg/L). In vivo, xanthotoxol inhibits predatory mouse and rat killing behavior in dogs and cats when administered at doses ranging from 3 to 100 mg/kg and 5 to 20 mg/kg, respectively. It reduces amphetamine-induced hypermobility in mice and hamsters. Xanthotoxol (5 and 10 mg/kg) reduces brain edema, neutrophil infiltration, blood-brain barrier disruption, production of IL-1β, TNF-α, IL-8, and nitric oxide (NO), and levels of intercellular adhesion molecule-1 (ICAM-1) and E-selectin in a rat model of focal cerebral ischemia.화학적 성질
Dark Brown Solid용도
Xanthotoxol is a hydroxylated psoralen that inhibits neutrophil infiltration and brain edema induced by focal cerebral ischemia-reperfusion injury in rats. A potentially useful antiarrhythmic agent. It has been show n to be effective in the prevention of ventricular fibrillation of mice induced by chloroform, of rats induced by calcium chloride, and in treatment of rat arrhythmia induced by aconitine. Recent stud ies show that it may also have antioxidant and anticancer activities.XANTHOTOXOL 준비 용품 및 원자재
원자재
오스뮴산
7-하이드록시쿠마린
무수초산
아세톤
인산
과산화 수소
황산 나트륨
탄산 칼륨
1.4-다이옥세인
염화알루미늄
초산에틸
과요드산 칼륨
브롬화알릴
메틸알콜
수산화나트륨
피리딘
N,N-디에틸아닐린
준비 용품
XANTHOTOXOL 공급 업체
글로벌( 190)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu Greenpure Biopharma CO.,Ltd | 18283602253 |
jancyzheng@gcgreenpure.com | China | 952 | 58 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 |
sales@biopurify.com | China | 3424 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 |
sales@pioneerbiotech.com | China | 3000 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 |
ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 |
1012@dideu.com | China | 3422 | 58 |