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(S)-1-Boc-3-methylpiperazine

(S)-1-Boc-3-methylpiperazine 구조식 이미지

카스 번호:: 147081-29-6

상품명:: (S)-1-Boc-3-methylpiperazine

동의어(영문):: tert-butyl (S)-3-methylpiperazine-1-carboxylate;(S)-1-BOC-3-METHYLPIPERAZINE;(S)-TERT-BUTYL 3-METHYLPIPERAZINE-1-CARBOXYLATE;(S)-4-Boc-2-methylpiperazine;4-HYDROXY-7-METHOXYQUINOLINE-2-CARBOXYLIC ACID;4-Hydroxy-7-methoxy-2-quinolinecarboxylic acid;CPD2809-SM;(3S)-3-MethyL;(S)-4-N-BOC-2-METHYL;Sotorasib Impurity 2

CBNumber:: CB9458934

분자식:: C10H20N2O2

포뮬러 무게:: 200.28

MOL 파일:: 147081-29-6.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 342

(S)-1-Boc-3-methylpiperazine 속성

녹는점: 40-45 °C

알파: -16 º (c=1 in dioxane)

끓는 점: 268.7±15.0 °C(Predicted)

밀도: 0.997±0.06 g/cm3(Predicted)

저장 조건: Keep in dark place,Inert atmosphere,2-8°C

산도 계수 (pKa): 8.52±0.40(Predicted)

물리적 상태: 결정성 분말

색상: 흰색에서 노란색으로

optical activity: [α]/D -16±2°, c = 1 in dioxane

감도: Air Sensitive

InChI: InChI=1S/C10H20N2O2/c1-8-7-12(6-5-11-8)9(13)14-10(2,3)4/h8,11H,5-7H2,1-4H3/t8-/m0/s1

InChIKey: FMLPQHJYUZTHQS-QMMMGPOBSA-N

SMILES: N1(C(OC(C)(C)C)=O)CCN[C@@H](C)C1

CAS 데이터베이스: 147081-29-6(CAS DataBase Reference)

안전

위험 및 안전 성명
위험 및 사전주의 사항 (GHS)

위험품 표기	Xi
위험 카페고리 넘버	37/38-41-34
안전지침서	26-39-45-36/37/39
유엔번호(UN No.)	3259
WGK 독일	3
F 고인화성물질	10-34
HS 번호	29335990

그림문자(GHS):

신호 어:

Danger

유해·위험 문구:

암호	유해·위험 문구	위험 등급	범주	신호 어	P- 코드
H315	피부에 자극을 일으킴	피부부식성 또는 자극성물질	구분 2	경고	P264, P280, P302+P352, P321,P332+P313, P362
H318	눈에 심한 손상을 일으킴	심한 눈 손상 또는 자극성 물질	구분 1	위험	P280, P305+P351+P338, P310
H335	호흡 자극성을 일으킬 수 있음	특정 표적장기 독성 - 1회 노출;호흡기계 자극	구분 3	경고

예방조치문구:

P280	보호장갑/보호의/보안경/안면보호구를 착용하시오.
P302+P352	피부에 묻으면 다량의 물로 씻으시오.

NFPA 704

	1
3		1

(S)-1-Boc-3-methylpiperazine C화학적 특성, 용도, 생산

개요

(S)-1-Boc-3-methylpiperazine is a hydrophobic compound that is structurally modified from the tetracyclic family of drugs. It has been shown to inhibit tumor cell growth by binding to the oncogene, KRASG12C, and downregulating its expression. This compound also inhibits cancer cell growth through the inhibition of the PI3K/AKT signaling pathway. The pharmacological effects of (S)-1-Boc-3-methylpiperazine are dependent on its ability to bind with high affinity to KRASG12C and inhibit its activity.

화학적 성질

colorless to yellow liquid

용도

Laboratory chemicals, Manufacture of substances.

(S)-1-Boc-3-methylpiperazine 준비 용품 및 원자재

원자재

준비 용품

UCB9608

(S)-1-Boc-3-methylpiperazine 공급 업체

글로벌( 342)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Shanghai Boc Chemical Co., Ltd.	021-34975602; +8618721111801	shangli@bocchem.com	China	138	58
AstaTech(Chengdu) Biopharmaceutical Corp.	+86-02882666559 +86-15884417729	gjpu@astatech.com.cn	China	308	58
Golden Pharma Co., Limited	+undefined18958062155	sales@zjgoldpharm.com	China	5905	58
Changzhou AniKare Pharmatech Co., Ltd.	+86-0519-8359-8696 +8618018249389	sales@anikare.com	China	8382	58
Shanghai UCHEM Inc.	+862156762820 +86-13564624040	sales@myuchem.com	China	6710	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7845	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Chembon Pharmaceutical Co., Ltd.	+86-28-8425-2981		CHINA	724	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58

(S)-1-Boc-3-methylpiperazine 관련 검색:

(S)-1-Boc-3-benzylpiperazine (S)-tert-butyl 3-formylpiperidine-1-carboxylate (3S)-3-AMinoazepane-1-carboxylic Acid tert-Butyl Ester (S)-1-N-Boc-3-ethylpiperazine (S)-1-BOC-3-PROPYLPIPERAZINE R-N-4-Boc-N-1-Cbz-2-piperazine carboxylic acid N-4-Boc-2-piperazinecarboxylic acid (S)-1-Boc-3-methylpiperazine 1-BOC-3,5-DIMETHYL-PIPERAZINE t-Butyl(2R,5S)-2,5-dimethylpiperazine-1-carboxylate (R)-4-N-Boc-piperazine-2-carboxylic acid methyl ester (R)-1-BOC-3-(Hydroxymethyl)piperazine (S)-2-tert-Butylcarboxamide-4-tert-butoxycarbonyl piperazine (1S,4S)-2-BOC-2,5-DIAZABICYCLO[2.2.1]HEPTANE (S)-1-N-Boc-2-methylpiperazine 4-N-Boc-2-Methyl-piperazine 1-Boc-2-Methylpiperazine (R)-1-Boc-3-methylpiperazine