SB216763
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SB216763 속성
- 녹는점
- 287-288.6 °C(lit.)
- 끓는 점
- 598.1±50.0 °C(Predicted)
- 밀도
- 1.47±0.1 g/cm3(Predicted)
- 저장 조건
- -20°C
- 용해도
- DMSO: 20mg/mL, 가용성
- 물리적 상태
- 주황색 고체
- 산도 계수 (pKa)
- 7.27±0.60(Predicted)
- 색상
- 오렌지 레드
- 색상
- 오렌지색
- 안정성
- 최대 3개월 동안 -20°의 DMSO에 보관
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
SB216763 C화학적 특성, 용도, 생산
용도
SB 216763 is a potent and selective cell permeale ATP-competitive inhibitor of GSK3a. It stimulates glycogen synthesis in Chang human liver cells.생물학적 활성
Potent and selective glycogen synthase kinase-3 (GSK-3) inhibitor (K i = 9 nM for GSK-3 α ); competes with ATP. Has minimal activity against 24 other protein kinases (IC 50 > 10 μ M). Stimulates glycogen synthesis, gene transcription and is neuroprotective.Biochem/physiol Actions
SB-216763 is a small molecule that competes with ATP and potently inhibits the activity α and β isozymes of GSK-3. It acts as neuroprotectant and prevents neuronal cell death induced by PI3-kinase pathway. It also delays preconditioning, reduces infarct size and prevents cardiac ischemia.SB216763 준비 용품 및 원자재
원자재
준비 용품
SB216763 공급 업체
글로벌( 179)공급 업체
공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32836 | 60 |
career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29888 | 58 |
Biochempartner | 0086-13720134139 |
candy@biochempartner.com | CHINA | 967 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39916 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49392 | 58 |
Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 |
1026@dideu.com | China | 23899 | 58 |
Finetech Industry Limited | +86-27-87465837 +8618971612321 |
info@finetechnology-ind.com | China | 9640 | 58 |
Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 |
info@dycnchem.com | China | 52861 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 |
sales@sarms4muscle.com | China | 10522 | 58 |
Hong Kong Tiansheng New Material Trading Co., Ltd | +8617320695765 |
zxx@hktiansheng.com | China | 981 | 58 |
SB216763 관련 검색:
카월 카페스톨
WIN 55,212-2 MESYLATE
SB 225002
SB 743921
2-(5-Benzo[1,3]dioxol-5-yl-2-tert-butyl-3H-imidazol-4-yl)-6-methylpyridine hydrate hydrochloride
Ispinesib
4-BENZYL-2-METHYL-1,2,4-THIADIAZOLIDINE-3,5-DIONE
SB 415286
1-AZAKENPAULLONE
SEDANOLIDE
S-[N-(3-PHENYLPROPYL)(THIOCARBAMOYL)]-L-CYSTEINE
2-THIO(3-IODOBENZYL)-5-(1-PYRIDYL)-[1,3,4]-OXADIAZOLE
MK-2206 2HCl
Saracatinib
LDE225 (NVP-LDE225,Erismodegib)
2,6-PYRIDINEDIAMINE, N6-[2-[[4-(2,4-DICHLOROPHENYL)-5-(1H-IMIDAZOL-1-YL)-2-PYRIMIDINYL]AMINO]ETHYL]-3-NITRO-
Ibrutinib