ChemicalBook >제품 카탈로그 >생화학 공학>억제제>GPCR & G 단백질>LPA 수용체 길항제>KI16425

KI16425

KI16425 구조식 이미지

카스 번호:: 355025-24-0

상품명:: KI16425

동의어(영문):: CS-88;KI-6425;Debio 0719;Ki16425, >=98%;KI16425 USP/EP/BP;KI-16425; KI 16425;Ki16425 (Debio 0719);KI16425;KI-16425; KI 16425;Ki 16425, competitive, potent and reversible antagonist to LPA;Ki 16425, 98%, competitive, potent and reversible antagonist to LPA

CBNumber:: CB9497429

분자식:: C23H23ClN2O5S

포뮬러 무게:: 474.96

MOL 파일:: 355025-24-0.mol

MSDS 파일:: SDS

속성

안전

용도

공급 업체 107

KI16425 속성

녹는점: 59.5-60.5 °C

끓는 점: 623.7±55.0 °C(Predicted)

밀도: 1.353

저장 조건: -20°C

용해도: DMSO: 16mg/mL

물리적 상태: 고체

물리적 상태: 단단한 모양

산도 계수 (pKa): 4.32±0.10(Predicted)

색상: 하얀색

안전

위험품 표기	Xi
위험 카페고리 넘버	36/37/38
안전지침서	26-36
WGK 독일	3
HS 번호	29349990

KI16425 C화학적 특성, 용도, 생산

개요

Lysophosphatidic acid (LPA) is a bioactive lipid mediator that signals through five distinct G protein-coupled receptors (LPA_1-5). Ki16425 is a LPA receptor antagonist with selectivity for LPA₁ and LPA₃. It exhibits K_i values of 0.34, 6.5, and 0.93 μM for the human LPA₁, LPA₂, and LPA₃ receptors, respectively, as determined by measuring inositol phosphate production in RH7777-transfected cells. Ki1642, at 10 μM, significantly blocks the response of a variety of cancer cell lines to LPA-induced cell migration.

용도

Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3.

Biochem/physiol Actions

Ki 16425 possesses a short-lived inhibitory activity. It has been studied that Ki 16425 is effective in the inhibition of neuropathic pain‐like behaviors.

KI16425 준비 용품 및 원자재

원자재

준비 용품

KI16425 공급 업체

글로벌( 107)공급 업체

공급자	전화	이메일	국가	제품 수	이점
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	47465	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10523	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6393	58
LEAP CHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	24738	58

KI16425 관련 검색:

Tofacitinib citrate 42-(Dimethylphosphinate)rapamycin MG-132 PD 98059 LY 2157299 Olaparib 3,5-DIMETHYL-4-ISOXAZOLEMETHANAMINE KI16425 N-(4-ISOXAZOLYL)FORMAMIDE 4-ISOXAZOLAMINE