6-METHYLAMINOPURINE 9-RIBOFURANOSIDE

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 구조식 이미지
카스 번호:
1867-73-8
상품명:
6-METHYLAMINOPURINE 9-RIBOFURANOSIDE
동의어(영문):
N6-Me-A;CS-1297;N6-Me-rA;N6-Me-Ar;NSC-29409;N6-Me-Adenosine;N-Methyladenosine;Adenosine, N-methyl-;N6,N6-Methyladenosin;Adenosine Impurity 15
CBNumber:
CB9503892
분자식:
C11H15N5O4
포뮬러 무게:
281.27
MOL 파일:
1867-73-8.mol

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 속성

녹는점
172 °C
끓는 점
649.1±65.0 °C(Predicted)
밀도
1.85±0.1 g/cm3(Predicted)
저장 조건
Keep in dark place,Sealed in dry,2-8°C
용해도
DMSO (약간 용해됨), 메탄올(약간 용해됨,가열, 초음파 처리)
물리적 상태
가루
산도 계수 (pKa)
13.12±0.70(Predicted)
안정성
흡습성
안전
  • 위험 및 안전 성명
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
예방조치문구:
NFPA 704
0
2 0

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE C화학적 특성, 용도, 생산

개요

N6-Methyladenosine is an adenosine analog. It inhibits epinephrine-induced contraction of isolated guinea pig ileum and thoracic aorta when used at a concentration of 10 μM. N6-Methyladenosine (1 mg/kg, i.v.) decreases arterial blood pressure and renal blood flow and increases peripheral resistance in anesthetized dogs. It also inhibits tumor growth in the C3H/ST and C3HB/ST mouse models of spontaneous mammary adenocarcinomas. N6-Methyladenosine is also the most prevelant mRNA modification in eukaryotes and has roles in cell viability and development.

용도

N6-Methyladenosine is the most common internal modification of eukaryotic mRNA. The result of this modification is specifically recognized mRNA in the cytoplasm which regulates mRNA stability.N6-Methyladenosine is made when a protein complex containin the writer enzyme METTL3 adds a methyl group to adenosine. Two different eraser enzymes ALKBH5 and FTO can remove a methyl group to turn m6A bach into adenosine.

정의

ChEBI: A methyladenosine compound with one methyl group attached to N6 of the adenine nucleobase.

6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 준비 용품 및 원자재

원자재

준비 용품


6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 공급 업체

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