tert-Butyl carbazate
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tert-Butyl carbazate 속성
- 녹는점
- 39-42 °C (lit.)
- 끓는 점
- 63-65 °C/0.1 mmHg (lit.)
- 밀도
- 1.02
- 굴절률
- 1.4496 (estimate)
- 인화점
- 197 °F
- 저장 조건
- Keep in dark place,Inert atmosphere,Store in freezer, under -20°C
- 용해도
- 에탄올과 메탄올에 용해됩니다.
- 산도 계수 (pKa)
- 10.74±0.20(Predicted)
- 물리적 상태
- 결정질 덩어리
- 색상
- 흰색에서 약간 노란색
- 감도
- Moisture Sensitive
- BRN
- 1756967
- InChIKey
- DKACXUFSLUYRFU-UHFFFAOYSA-N
- CAS 데이터베이스
- 870-46-2(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | T-F,T,F | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 48-36/37/38-24/25-11 | ||
| 안전지침서 | 45-36/37/39-16-24/25 | ||
| 유엔번호(UN No.) | 1325 | ||
| WGK 독일 | 3 | ||
| F 고인화성물질 | 21 | ||
| TSCA | Yes | ||
| 위험 등급 | 4.1 | ||
| 포장분류 | III | ||
| HS 번호 | 29280090 |
tert-Butyl carbazate C화학적 특성, 용도, 생산
화학적 성질
White to pale yellow lumps용도
tert-Butyl carbazate is used in a palladium-catalyzed cross-coupling with vinyl halides to prepare N-Boc-N-alkenylhydrazines. It is utilized in solid phase peptide synthesis and in the optical purity determination of alfa-amino aldehyde. It reacts with aldehydes to get hydrazones, which finds application as an intermediate in the synthesis of HIV-1 protease inhibitors. In addition to this, it is used as a starting material for the preparation of BOC-azide, sulfonic and carboxylic hydrazides.Purification Methods
Distil it in a Claisen flask with a water or oil bath at ca 80o. After a couple of drops have distilled, the carbazate is collected as an oil which solidifies to a snow white solid. It can be crystallised with 90% recovery from a 1:1 mixture of pet ether (b 30-60o) and pet ether (b 60-70o). [Carpino et al. Org Synth Coll Vol V 166 1973, Caprino et al. Org Synth 44 20 1964, Beilstein 3 IV 175.]tert-Butyl carbazate 준비 용품 및 원자재
원자재
하이드라진 수화물
디 -Tert- 부틸 디 카보네이트
하이드라진, 모노수화물
이소프로필알코올
N-Boc-L-Histidine
N,N'-Di-tert-butoxycarbonyl-L-histidine
준비 용품
PYRIDIN-2-YLMETHYL-HYDRAZINE
PYRIDIN-3-YLMETHYL-HYDRAZINE
(2-METHOXY-1-METHYL-ETHYL)-HYDRAZINE
PYRIDIN-4-YLMETHYL-HYDRAZINE
CYCLOBUTYLHYDRAZINE
3,5-DIMETHYL-1H-PYRAZOLE-4-CARBOXYLIC ACID
DI-TERT-BUTYL HYDRAZODICARBOXYLATE
tert-butyl azidoformate
1-N-Boc-2-Methylhydrazine
tert-butyl 2-cyano-1H-pyrrol-1-ylcarbaMate
1-Boc-2-isopropylhydrazine
Des-N-(methoxycarbonyl)-L-tert-leucine Bis-Boc Atazanavir
TERT-BUTYL N-(TERT-BUTOXYCARBONYLOXY)CARBAMATE
tert-Butyl 2-methylcarbazate
TERT-BUTYL 2-CYCLOHEXYLHYDRAZINECARBOXYLATE
tert-Butyl carbazate 공급 업체
글로벌( 612)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| GenChem & GenPharm (Changzhou) Co., Ltd. | +86-86020003 +86-18861157602 |
sales03@genchem.cn | China | 79 | 58 |
| Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 |
info@pharmachemm.com | China | 246 | 58 |
| Changzhou Ditong Chemical Co.,Ltd | +86-0519-88299272 |
info@edengenechem.com | China | 2169 | 58 |
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12457 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 |
daisy@anhuiruihan.com | China | 994 | 58 |
| Hebei Weimiao Import and Export Trade Co., Ltd. | +undefined19948166995 |
sale01@hbweimiao.com | China | 67 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7613 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 |
nova@sh-teruiop.com | China | 525 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +86-86-1913198-3935 +8617331935328 |
sales03@chemcn.cn | China | 951 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 |
sales@capotchem.com | China | 29797 | 60 |