트리에틸 아인산염
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트리에틸 아인산염 속성
- 녹는점
- -112°C
- 끓는 점
- 65 °C
- 밀도
- 0.969 g/mL at 25 °C(lit.)
- 증기압
- <6 hPa (20 °C)
- 굴절률
- n
20/D 1.413(lit.)
- 인화점
- 130 °F
- 저장 조건
- Flammables area
- 용해도
- 클로로포름(약간 용해됨), 디클로로메탄(약간 용해됨), 메탄올(약간 용해됨)
- 물리적 상태
- 액체
- 색상
- 무색의
- Specific Gravity
- 0.969
- 냄새
- 특유의, 불쾌한, 인산염 냄새
- 폭발한계
- 3.75-42.5%(V)
- 수용성
- 약간 용해됨
- 감도
- Air & Moisture Sensitive
- Hydrolytic Sensitivity
- 7: reacts slowly with moisture/water
- BRN
- 956578
- Dielectric constant
- 10.9（65℃）
- 안정성
- 공기 민감성, 수분 민감성
- CAS 데이터베이스
- 122-52-1(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험품 표기 | Xn | ||
|---|---|---|---|
| 위험 카페고리 넘버 | 10-22-36/37/38-20/22 | ||
| 안전지침서 | 16-26-36 | ||
| 유엔번호(UN No.) | UN 2323 3/PG 3 | ||
| WGK 독일 | 1 | ||
| RTECS 번호 | TH1130000 | ||
| F 고인화성물질 | 10-23 | ||
| 자연 발화 온도 | 250 °C | ||
| TSCA | Yes | ||
| HS 번호 | 2920 24 00 | ||
| 위험 등급 | 3 | ||
| 포장분류 | III | ||
| 유해 물질 데이터 | 122-52-1(Hazardous Substances Data) | ||
| 독성 | LD50 orl-rat: 1840 mg/kg JACTDZ 1,218,92 | ||
| 기존화학 물질 | KE-28705 |
트리에틸 아인산염 C화학적 특성, 용도, 생산
물성
분자량(MW) 166.1565 ;비중 0.97; 끓는점(°C) 156;
인화점(°C) 52;
성상 및 특성 피부와 눈에 자극을 일으키는 가연성 액체.
용도
인(P)이 포함된 화학무기(신경가스)의 원료- 난연제, 농약, 의약품, 산화방지제등.화학적 성질
Triethyl phosphite is a clear colorless liquid with a strong foul odor. Insoluble in water; soluble in alcohol and ether. Combustible.Vapors heavier than air.용도
Triethyl phosphite is an organophosphorus compound. It is used as a reducing agent; can react with electrophiles to form phosphonates or phosphates; forms a stable complex with copper(I) iodide.Triethyl phosphite is a very good nucleophile. The carbon adjacent to the bromine is the most electrophilic position, and phosphorus is the only nucleophile. Triethyl phosphite displaces the bromine in an SN2-like process, and back attack by the bromide which is released generates a phosphonate product, in which the α-protons are strongly acidic.
제조 방법
Triethyl phosphite is produced in a closed system by reaction of phosphorous trichlorid and ethanol in the presence of an inorganic or organic base. The product is purified by distillation (Bayer AG, 2002a).
Triethyl phosphite is exclusively used as an intermediate for the manufacturing of different products: flame retardants (about 60 %), optical brighteners (about 15 %), pesticides (about 15 %), antioxidants (about 5 %), and pharmaceuticals (about 5 %).
화학 반응
This reaction is currently used for the preparation of synthetically useful phosphonate reagents employed in modified retinal studies. Thus, diethyl 3-alkoxycarbonyl-2-propenylphosphonates are prepared in 72-91% yields by the reaction of methyl or ethyl 4-bromocrotonates with triethyl phosphite at 150-160°C. Similarly, diethyl 3-(ethoxycarbonyl)-2 methyl-2-propenylphosphonate is prepared in 81% yield from triethyl phosphite and ethyl 3-methyl-4-chlorocrotonate by heating at 180- 200°C.The diethyl (E)- and (Z)-3-ethoxycarbonyl-3 fluoro-2 -methyl-2-propenylphosphonates are respectively obtained from triethyl phosphite and (E)- or (Z)-4-bromo-2-fuoro-3-methyl-2-butenoates at 140°C.반응 프로필
Triethyl phosphite is colorless, moderately toxic liquid, combustible. Flammable when exposed to heat or flame. When heated to decomposition Triethyl phosphite emits toxic fumes of oxides of phosphorus [Lewis, 3rd ed., 1993, p. 1271].건강위험
Exposure to high concentrations may cause headache, nausea, and dizziness due to reduced chlolinesterase activity.화재위험
Special Hazards of Combustion Products: May form hazardous decomposition products.Safety Profile
Moderately toxic by ingestion. A skin and eye irritant. Flammable liquid when exposed to heat, sparks, or flame. When heated to decomposition it emits toxic fumes of POx.트리에틸 아인산염 준비 용품 및 원자재
원자재
준비 용품
2-(2,3-DIHYDRO-1BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ETHANAMINE
2-[2-[4-[2-(4-시아노페닐)비닐]페닐]비닐]벤조니트릴
2-[2-(2-thienyl)ethyl]benzoic acid
DIETHYL (N-METHOXY-N-METHYLCARBAMOYLMETHYL)PHOSPHONATE
Phosphite
포노포스
3,3-사메틸렌 글루타릭 산
4-Benzofurazancarboxaldehyde
(2-Aminoethyl)phosphonic acid
1,2-디(4-피리딜)에틸렌
DIETHYL(4-NITROBENZYL)PHOSPHONATE
1-CYCLOPENTYLIDENE-PROPAN-2-ONE
SPIRO[4.5]DECANE-7,9-DIONE
4-Oxo-9,10-dihydro-4H-benzo(4,5)-cyclohepta-(1,2b)thiophene
2,2'-((1,1'-비페닐)-4,4'-디일디-2,1-에텐디일)비스- 벤젠술폰 산 디나트륨 염
Foscarnet sodium
2-METHYLCYCLOPROPANECARBOXYLIC ACID
메틸(7-)-1,6-옥타디엔
N-(2-Methylpropylidene)-butylamine
2-(b-(2-Thienyl)vinyl)benzoicacid
2-(2,3-DIHYDRO-1-BENZENESULFONYL-PYRROLO[2,3-B]PYRIDIN-3-YL)ACETONITRILE
Optical Brighter FP127
THIOPHEN-2-YLMETHYL-PHOSPHONIC ACID DIETHYL ESTER
Propylphosphonic anhydride
제라닉애씨드
트리에틸 아인산염 공급 업체
글로벌( 292)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 |
sales@hbmojin.com | China | 12456 | 58 |
| Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 |
info@fdachem.com | China | 7845 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 |
info@tianfuchem.com | China | 21691 | 55 |
| career henan chemical co | +86-0371-86658258 |
sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 |
alice@crovellbio.com | China | 8823 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 |
linda@hubeijusheng.com | CHINA | 22968 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 |
sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 |
sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49390 | 58 |