사르코신

사르코신
사르코신 구조식 이미지
카스 번호:
107-97-1
한글명:
사르코신
동의어(한글):
사르코신;사코신
상품명:
Sarcosine
동의어(영문):
Sar;Methylglycine;N-METHYLGLYCINE;H-SAR-OH;Sarcosin;SAR-OH;N-ME-GLY-OH;Methyl-glycocoll;H-MEGLY-OH;CH3NHCH2COOH
CBNumber:
CB9712144
분자식:
C3H7NO2
포뮬러 무게:
89.09
MOL 파일:
107-97-1.mol
MSDS 파일:
SDS

사르코신 속성

녹는점
208-212 °C (dec.)(lit.)
끓는 점
165.17°C (rough estimate)
밀도
1.1948 (rough estimate)
벌크 밀도
600kg/m3
굴절률
1.4368 (estimate)
인화점
>100℃
저장 조건
Store below +30°C.
용해도
H2O: 1 M at 20 °C
물리적 상태
결정 또는 분말
산도 계수 (pKa)
2.21(at 25℃)
색상
무색 또는 흰색에서 노란색까지
수소이온지수(pH)
6.1 (100g/l, H2O, 20℃)
수용성
1480g/L(20℃)
감도
Hygroscopic
Merck
14,8373
BRN
1699442
주요 응용
펩타이드 합성
화장품 원료 기능
피부 컨디셔닝
InChI
1S/C3H7NO2/c1-4-2-3(5)6/h4H,2H2,1H3,(H,5,6)
InChIKey
FSYKKLYZXJSNPZ-UHFFFAOYSA-N
SMILES
CNCC(O)=O
CAS 데이터베이스
107-97-1(CAS DataBase Reference)
NIST
Sarcosine(107-97-1)
EPA
Sarcosine (107-97-1)
CAS Number Unlabeled
107-97-1
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi
위험 카페고리 넘버 36/37/38
안전지침서 24/25-36-26
WGK 독일 1
RTECS 번호 VQ2897000
F 고인화성물질 3
TSCA TSCA listed
HS 번호 29224995
스토리지 클래스 11 - Combustible Solids
기존화학 물질 KE-24123
그림문자(GHS): Exclamation Mark (GHS07)
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H302 삼키면 유해함 급성 독성 물질 - 경구 구분 4 경고 P264, P270, P301+P312, P330, P501
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P305+P351+P338 눈에 묻으면 몇 분간 물로 조심해서 씻으시오. 가능하면 콘택트렌즈를 제거하시오. 계속 씻으시오.
NFPA 704
1
1 0

사르코신 MSDS


H-Sar-OH

사르코신 C화학적 특성, 용도, 생산

화학적 성질

White crystalline powder

용도

Sarcosine can improve people's intelligence, especially for exams such as the students need to temporarily increase the effectiveness of intelligence is more obvious. sarcosine can increase muscle strength and anaerobic explosiveness.To prevent damage caused by the brain injury. Sarcosine can effectively improve athletic performance,power, and shorten muscle recovery time.

용도

Sarcosine is an important component for the production of the amino acid glycine and a byproduct of glycine breakdown. In the body, it is produced by converting dietary choline to glycine or breaking down methionine into glycine. It can also be synthesized in the laboratory with chloroacetic acid and methylamine. Sarcosine has a unique mild sweetness. Since a derivative of creatine helps prevent tooth decay and causes foam, it acts as an ingredient in toothpaste. Sarcosine can also be used as a drug, and research over the past 20 years has revealed its role in treating mental health disorders such as schizophrenia and depression.

정의

ChEBI: Sarcosine is a N-alkylglycine that is the N-methyl derivative of glycine. It is an intermediate in the metabolic pathway of glycine. It has a role as a glycine transporter 1 inhibitor, a glycine receptor agonist, a human metabolite, an Escherichia coli metabolite and a mouse metabolite. It is a N-alkylglycine, a N-methyl-amino acid and a member of N-methylglycines. It is a conjugate base of a sarcosinium. It is a conjugate acid of a sarcosinate. It is a tautomer of a sarcosine zwitterion.

일반 설명

Deliquescent crystals or powder. Has a sweetish taste.

공기와 물의 반응

Deliquescent. Water soluble.

반응 프로필

Sarcosine is an amide. Amides/imides react with azo and diazo compounds to generate toxic gases. Flammable gases are formed by the reaction of organic amides/imides with strong reducing agents. Amides are very weak bases (weaker than water). Imides are less basic yet and in fact react with strong bases to form salts. That is, they can react as acids. Mixing amides with dehydrating agents such as P2O5 or SOCl2 generates the corresponding nitrile. The combustion of these compounds generates mixed oxides of nitrogen (NOx). Sarcosine is incompatible with acids. .

화재위험

Flash point data for Sarcosine are not available. Sarcosine is probably combustible.

생물학적 활성

Endogenous inhibitor of GlyT1 that displays antipsychotic activity. Potentiates the action of glycine on the NMDA glycine binding site.

부작용

Sarcosine, a dietary supplement, is generally considered harmless with minimal side-effects. However, some individuals report experiencing euphoria and hyperactivity after consuming it. Men taking sarcosine may have an increased risk for prostate cancer, while others may experience sleeplessness, irritability, and headaches.
Sarcosine: The Super Nutrient That May Reverse Schizophrenia Symptoms

Purification Methods

Crystallise sarcosine from absolute EtOH, 95% EtOH or H2O. It sublimes at 180-185o/0.3mm with 99.1% recovery [Gross & Gradsky J Am Chem Soc 77 1678 1955]. [Cocker & Harris J Chem Soc 1291 1940, Cocker & Lapworth J Chem Soc 1897 1931, Greenstein & Winitz The Chemistry of the Amino Acids J. Wiley, Vol 3 p 2750 1961, Beilstein 4 III 1121, 4 IV 2363.]

사르코신 준비 용품 및 원자재

원자재

준비 용품


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