RO 106-9920

RO 106-9920 구조식 이미지
카스 번호:
62645-28-7
상품명:
RO 106-9920
동의어(영문):
RO 106-9920;Ro 106 9920,Ro 1069920;Ro 106-9920 DISCONTINUED;TETRAZOLOPYRIDAZINE-PHENYLSULFOXIDE;6-(PHENYLSULFINYL)TETRAZOLO[1,5-B]PYRIDAZINE;Tetrazolo[1,5-b]pyridazine, 6-(phenylsulfinyl)-
CBNumber:
CB9728932
분자식:
C10H7N5OS
포뮬러 무게:
245.26
MOL 파일:
62645-28-7.mol
MSDS 파일:
SDS

RO 106-9920 속성

저장 조건
Store at +4°C
용해도
Soluble to 5 mM in ethanol and to 100 mM in DMSO
물리적 상태
흰색 고체

안전

RO 106-9920 C화학적 특성, 용도, 생산

용도

Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.

생물학적 활성

Inhibitor of NF- κ B activation, possibly via selective inhibition of LPS- and TNF- α -induced I κ B α ubiquitination (IC 50 = 3 μ M). Blocks subsequent production of TNF- α , IL-1 β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo . Also weakly inhibits EGFR, 5-lipoxygenase and iNOS.

RO 106-9920 준비 용품 및 원자재

원자재

준비 용품


RO 106-9920 공급 업체

글로벌( 61)공급 업체
공급자 전화 이메일 국가 제품 수 이점
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181
sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788
jkinfo@jkchemical.com China 94838 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037
3bsc@sina.com China 15848 69
Chemsky (shanghai) International Co.,Ltd 021-50135380
shchemsky@sina.com China 15421 60
EMMX Biotechnology LLC 888-539-0666
info@emmx.com United States 8449 60
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684
sales@rrkchem.com China 55717 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
sales@chemegen.com China 11289 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912
order@med-bio.cn China 8141 58
Energy Chemical 021-58432009 400-005-6266
marketing@energy-chemical.com China 44941 58

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