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모넨신

모넨신
모넨신 구조식 이미지
카스 번호:
17090-79-8
한글명:
모넨신
동의어(한글):
모넨신;2-(5-에틸테트라하이드로-5-(테트라하이드로-3-메틸-5-(테트라하이드로-6-하이드록시-6-(하이드록시메틸)-3,5-다이메틸-2H-피란-2-일)-2-퓨릴)-2-퓨릴)- 9-하이드록시-베타-메톡시-알파,감마,2,8-테트라메틸-1,6-다이옥사스파이로[4.5]데케인-7-뷰티르산;2-[2-에틸옥타하이드로-3'-메틸-5'-[테트라하이드로-6-하이드록시-6-(하이드록시메틸)-3,5-다이메틸-2H-피란-2-일][2,2'-바이퓨란]-5-일]-9-하이드록시-베타-메톡시-알파,감마,2,8-테트라메틸-1,6-다이옥사스파이로[4.5]데케인-7-뷰탄산의 입체이성질체;2-[5-에틸테트라하이드로-5-[테트라하이드로-3-메틸-5-[테트라하이드로-6-하이드록시-6-(하이드록시메틸)-3,5-다이메틸-2H-피란-2-일]-2-퓨릴]-2-퓨릴]-9-하이드록시-베타-메톡시-알파,감마,2,8-테트라메틸-1,6-다이옥사스파이로[4.5]데케인-7-뷰티르산;4-[2-[2-에틸-5’-(6-하이드록시-6-하이드록시메틸-3,5-다이메틸테트라하이드로피란-2-일)-3’-메틸옥타하이드로-[2,2’]바이퓨란일-5-일]-9-하이드록시-2,8-다이메틸-1,6-다이옥사스파이로[4.5]데크-7-일]-3-메톡시-2-메틸펜탄산;모넨스산
상품명:
Monensin
동의어(영문):
a3823a;monelan;MONENSIN;Romensin;elancoban;Monensin A;MONENSIN NA;Monensin 20%;monensicacid;MONENSIN(PURE)
CBNumber:
CB9748019
분자식:
C36H62O11
포뮬러 무게:
670.87
MOL 파일:
17090-79-8.mol

모넨신 속성

녹는점
103-105°C
알파
D +47.7°
끓는 점
608.24°C (rough estimate)
밀도
1.0773 (rough estimate)
굴절률
1.5465 (estimate)
저장 조건
2-8°C
산도 계수 (pKa)
6.6 (in 66% DMF)
CAS 데이터베이스
17090-79-8(CAS DataBase Reference)
EPA
Monensin (17090-79-8)

안전

위험품 표기 T
위험 카페고리 넘버 25
안전지침서 36/37/39-45
유엔번호(UN No.) UN 3462 6.1/PG 2
WGK 독일 3
RTECS 번호 JH2830000
위험 등급 6.1(a)
포장분류 II
유해 물질 데이터 17090-79-8(Hazardous Substances Data)
독성 LD50 of monensin complex in mice, chicks (mg/kg): 43.8 ± 5.2, 284 ± 47 orally (Haney, Hoehn)
기존화학 물질 KE-05-0885
유해화학물질 필터링 97-1-87
함량 및 규제정보 물질구분: 유독물질; 혼합물(제품)함량정보: 모넨신과 그 염류 및 그 중 모넨신으로서 8% 이상 함유한 혼합물

모넨신 C화학적 특성, 용도, 생산

화학적 성질

Crystallin Solid

용도

Monensin A is a polyether antibiotic first isolated from Streptomyces cinnamonensis in 1967. Monensin A is a broad-spectrum anticoccicidial antibiotic, also exhibiting antifungal and antiviral activity. Monensin A forms complexes with monovalent cations such as Li+, Na+, K+, Rb+, Ag+ and Tl+ and is thus able to transport these cations across lipid membranes of cells, playing an important role as an Na+/H+ antiporter. It blocks intracellular protein transport and is used in animals to prevent coccidiosis, promote growth and prevent bloat. Derivatives of monensin, monensin methyl ester and particularly monensin decyl ester, are used in ion selective electrodes.

용도

Poliether antibiotic. Coccidiostat

용도

Monensin (2) C36H62O11, a carboxylic acid which is used as its water-soluble sodium salt (Coban, Rumensin). Monensin is also used to treat histomoniasis. The polyether ionophoric antibiotics are capable of complexing and interfacing with specific alkali metal cations to render them lipid-soluble and diffusible across parasite mitochondrial membranes. Related useful polyether antibiotics are narasin and lasalocid (3, Lasalocid A, C34H54O8,).

상표명

Coban [as sodium salt] (Lilly);Rumensin [as sodium salt] (Lilly).

Safety Profile

Poison by ingestion and intraperitoneal routes. An eye and skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes.

모넨신 준비 용품 및 원자재

원자재

준비 용품


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BOC Sciences
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CONIER CHEM AND PHARMA LIMITED
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