D-Phenylalanine

D-Phenylalanine 구조식 이미지
카스 번호:
673-06-3
상품명:
D-Phenylalanine
동의어(영문):
PHENYLALANINE;d-phe;H-D-PHE-OH;D-Phe-OH;(R)-PHENYLALANINE;(R)-2-amino-3-phenylpropanoic acid;NSC 25005;nci-c60195;Endorphenyl;D-Phenylalanin
CBNumber:
CB9773699
분자식:
C9H11NO2
포뮬러 무게:
165.19
MOL 파일:
673-06-3.mol
MSDS 파일:
SDS

D-Phenylalanine 속성

녹는점
273-276 °C(lit.)
끓는 점
293.03°C (rough estimate)
알파
33.5 º (c=2, H2O)
밀도
1.1603 (rough estimate)
굴절률
34 ° (C=2, H2O)
저장 조건
Store at RT.
용해도
메탄올(약간 용해됨), 물(약간 용해됨)
물리적 상태
가루
산도 계수 (pKa)
2.2(at 25℃)
색상
흰색에서 황백색까지
수용성
27 g/L (20 ºC)
Merck
14,7271
BRN
2804068
안정성
안정적인. 강한 산화제, 산, 염기와 호환되지 않습니다.
InChIKey
COLNVLDHVKWLRT-MRVPVSSYSA-N
LogP
0.235 (est)
CAS 데이터베이스
673-06-3(CAS DataBase Reference)
EPA
D-Phenylalanine (673-06-3)
안전
  • 위험 및 안전 성명
  • 위험 및 사전주의 사항 (GHS)
위험품 표기 Xi,C
위험 카페고리 넘버 34
안전지침서 24/25-45-36/37/39-27-26
WGK 독일 3
RTECS 번호 AY7533000
위험 참고 사항 Irritant
TSCA Yes
HS 번호 29224995
독성 TDLo orl-hmn: 500 mg/kg/5W-I:GIT JACTDZ 1(3),124,82
그림문자(GHS): GHS hazard pictograms
신호 어: Warning
유해·위험 문구:
암호 유해·위험 문구 위험 등급 범주 신호 어 그림 문자 P- 코드
H315 피부에 자극을 일으킴 피부부식성 또는 자극성물질 구분 2 경고 GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 눈에 심한 자극을 일으킴 심한 눈 손상 또는 자극성 물질 구분 2A 경고 GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 호흡 자극성을 일으킬 수 있음 특정 표적장기 독성 - 1회 노출;호흡기계 자극 구분 3 경고 GHS hazard pictograms
예방조치문구:
P261 분진·흄·가스·미스트·증기·...·스프레이의 흡입을 피하시오.
P271 옥외 또는 환기가 잘 되는 곳에서만 취급하시오.
P280 보호장갑/보호의/보안경/안면보호구를 착용하시오.
NFPA 704
0
1 0

D-Phenylalanine MSDS


D-alpha-Amino-beta-phenylpropionic acid

D-Phenylalanine C화학적 특성, 용도, 생산

개요

D-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of enkephalin degradation by the carboxypeptidase A. Enkephalins are part of your body’s natural pain relief system. When they are broken down by enkephalinase, this contributes to the sensation of pain. D-Phenylalanine is specifically thought to be beneficial for reducing feelings of chronic pain. D-phenylalanine has been used with mixed results to treat chronic pain, including pain caused by rheumatoid arthritis. The primary use of D-phenylalanine as a health supplement is the relief of discomfort.

화학적 성질

White crystalline powder

용도

D-Phenylalanine, the stereoisomer of L-Phenylalanine (P319415) has been used in the synthesis of Schaeffer’s acid analogues as important structures in tuberculostatic design. They exhibit the ability to inhibit Mycobacterium tuberculosis type II dehydroquinase.

정의

ChEBI: D-phenylalanine is the D-enantiomer of phenylalanine. It is a phenylalanine and a D-alpha-amino acid. It is a conjugate base of a D-phenylalaninium. It is a conjugate acid of a D-phenylalaninate. It is an enantiomer of a L-phenylalanine. It is a tautomer of a D-phenylalanine zwitterion.

일반 설명

D-phenylalanine appears as needles or prisms.

공기와 물의 반응

Water soluble. Aqueous solutions are weakly acidic.

반응 프로필

D-alpha-Amino-beta-phenylpropionic acid may be light sensitive. D-alpha-Amino-beta-phenylpropionic acid reacts with strong oxidizing agents, acids and bases. . Act as weak acids in solution.

화재위험

Flash point data for D-alpha-Amino-beta-phenylpropionic acid are not available, however D-alpha-Amino-beta-phenylpropionic acid is probably combustible.

Safety Profile

Mildly toxic by intraperitoneal route. Human systemic effects by ingestion: nausea, hypermotility, diarrhea. When heated to decomposition it emits toxic fumes of NOx.

참고 문헌

https://www.alfa.com/en/catalog/A10572/
https://en.wikipedia.org/wiki/Phenylalanine
Christianson, D. W., et al. "Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. " Journal of Biological Chemistry264.22(1989):12849-53.

D-Phenylalanine 준비 용품 및 원자재

원자재

준비 용품


D-Phenylalanine 공급 업체

글로벌( 712)공급 업체
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Hangzhou FandaChem Co.,Ltd.
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