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D-Phenylalanine

D-Phenylalanine 구조식 이미지
카스 번호:
673-06-3
상품명:
D-Phenylalanine
동의어(영문):
d-phe;D-Phe-OH;673-06-3;NSC 25005;nci-c60195;H-D-PHE-OH;Endorphenyl;PHENYLALANINE;D-Phenylalanin;D-PHENYLALANINE
CBNumber:
CB9773699
분자식:
C9H11NO2
포뮬러 무게:
165.18914
MOL 파일:
673-06-3.mol

D-Phenylalanine 속성

녹는점
273-276 °C(lit.)
알파
33.5 º (c=2, H2O)
끓는 점
293.03°C (rough estimate)
밀도
1.1603 (rough estimate)
굴절률
34 ° (C=2, H2O)
저장 조건
Store at RT.
산도 계수 (pKa)
2.2(at 25℃)
물리적 상태
Powder
색상
White to off-white
수용성
27 g/L (20 ºC)
Merck
14,7271
BRN
2804068
안정성
Stable. Incompatible with strong oxidizing agents, acids, bases.
InChIKey
COLNVLDHVKWLRT-MRVPVSSYSA-N
CAS 데이터베이스
673-06-3(CAS DataBase Reference)
EPA
D-Phenylalanine(673-06-3)

안전

위험품 표기 Xi,C
위험 카페고리 넘버 34
안전지침서 24/25-45-36/37/39-27-26
WGK 독일 3
RTECS 번호 AY7533000
위험 참고 사항 Irritant
TSCA Yes
HS 번호 29224995

D-Phenylalanine C화학적 특성, 용도, 생산

개요

D-Phenylalanine, also known as D-alpha-Amino-beta-phenylpropionic acid, is a kind of non-proteinogenic amino acid. The biological function of D-phenylalanine remains unclear. However, it has certain anti-depressant, analgesic activities and pharmacological activity at niacin receptor II. The mechanism action of its analgesic activity seems to originate from its inhibition of enkephalin degradation by the carboxypeptidase A. It can also be used as pharmaceutical intermediates that are mainly used to treat, prevent osteoporosis, cardiovascular, diabetes and arterioscleros.

화학적 성질

White crystalline powder

용도

antidepressant

정의

ChEBI: The D-enantiomer of phenylalanine.

일반 설명

Needles or prisms.

공기와 물의 반응

Water soluble. Aqueous solutions are weakly acidic.

반응 프로필

D-alpha-Amino-beta-phenylpropionic acid may be light sensitive. D-alpha-Amino-beta-phenylpropionic acid reacts with strong oxidizing agents, acids and bases. . Act as weak acids in solution.

화재위험

Flash point data for D-alpha-Amino-beta-phenylpropionic acid are not available, however D-alpha-Amino-beta-phenylpropionic acid is probably combustible.

Safety Profile

Mildly toxic by intraperitoneal route. Human systemic effects by ingestion: nausea, hypermotility, diarrhea. When heated to decomposition it emits toxic fumes of NOx.

참고 문헌

https://www.alfa.com/en/catalog/A10572/
https://en.wikipedia.org/wiki/Phenylalanine
Christianson, D. W., et al. "Binding of D-phenylalanine and D-tyrosine to carboxypeptidase A. " Journal of Biological Chemistry264.22(1989):12849-53.

D-Phenylalanine 준비 용품 및 원자재

원자재

준비 용품


D-Phenylalanine 공급 업체

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