Abacavir sulfate manufacturers and suppliers

Abacavir sulfate suppliers

Properties

Melting point:: 222-225°C

storage temp.: 2-8°C

solubility: H2O: ≥17mg/mL

form: powder

color: white to tan

optical activity: [α]/D -30 to -40°, c = 0.5 in methanol

Water Solubility: 1.68ug/L(32 ºC)

BCS Class: 3

Safety Information

Symbol(GHS): GHS07,GHS08

Signal word: Warning

Hazard statements: H317-H319-H341-H351-H361

Precautionary statements: P201-P202-P280-P302+P352-P305+P351+P338-P308+P313

Hazard Codes: Xn

Risk Statements: 63-40

Safety Statements: 36/37

WGK Germany: 3

HS Code: 2933595960

Use

Abacavir sulfate was first launched as Ziagen in the US for the treatment of human immunodeficiency virus (HIV) infection, in combination with other antiretroviral drugs. Abacavir is a carbocyclic nucleoside reverse transcriptase inhibitor (nRTI); it is one of the most potent anti-HIV agents to date. The compound can be prepared by an enantioselective synthesis involving palladium-catalyzed coupling of a chloropurine with a carbocyclic allylic diacetate. In vitro, Abacavir is a potent and selective inhibitor of HIV-1 and HIV-2 replication.

You can find Abacavir sulfate suppliers, manufacturers, and distributors from countries such as CHINA, India and the United States here. Browse to the tetrahydrofuran product information displayed by the supplier, as well as the supplier's contact and capability information.