Acetylsalicylic acid manufacturers and suppliers

Acetylsalicylic acid suppliers

Properties

Melting point:: 134-136 °C (lit.)

Boiling point:: 272.96°C (rough estimate)

Density: 1.35

refractive index: 1.4500 (estimate)

Flash point:: 250 °C

storage temp.: 2-8°C

solubility: H₂O: 10 mg/mL at 37 °C

form: crystalline

color: white

pka: 3.5(at 25℃)

Water Solubility: 3.3 g/L (20 ºC)

Merck: 14,851

BRN: 779271

Exposure limits: ACGIH: TWA 5 mg/m3
NIOSH: TWA 5 mg/m3

BCS Class: 3

Stability:: Stable. Keep dry. Incompatible with strong oxidizing agents, strong bases, strong acids, various other compounds such as iodides, iron salts, quinine salts, etc.

InChIKey: BSYNRYMUTXBXSQ-UHFFFAOYSA-N

LogP: 1.190

Safety Information

Symbol(GHS): GHS07

Signal word: Warning

Hazard statements: H302

Precautionary statements: P264-P270-P301+P312-P501

Hazard Codes: Xn

Risk Statements: 22-36/37/38

Safety Statements: 26-36/37/39

RIDADR: UN 1851

WGK Germany: 1

RTECS: VO0700000

TSCA: Yes

HazardClass: 6.1

PackingGroup: III

HS Code: 29182210

Toxicity: LD50 orally in mice, rats: 1.1, 1.5 g/kg (Hart)

Use

Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

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